Morphometric classification and spatial organization of spiral ganglion neurons in the human cochlea: consequences for single fiber response to electrical stimulation.
Bottom Line: Furthermore, we found evidence of a spatial arrangement of perikarya and their accordant nuclei along the cochlea spiral.Cathodic stimulation was found to induce stronger variations of spikes while also leading to the lowest thresholds and longest latencies.Therefore, anodic stimulation leads to a more uniform excitation profile among SGCs with different cell body size.
Affiliation: Innsbruck Medical University, Department of Otorhinolaryngology, Laboratory for Inner Ear Biology, Anichstrasse 35, Innsbruck, Austria.Show MeSH
Mentions: These temporal parameters are displayed in Fig. 6 which demonstrates different spiking behavior when a selected model cell with d = 19.08 μm (which is the mean value of all evaluated diameters) is stimulated by electrode E1 with the four different pulse forms. The time courses of membrane potential of this cell are plotted for monophasic and biphasic threshold stimulations.
Affiliation: Innsbruck Medical University, Department of Otorhinolaryngology, Laboratory for Inner Ear Biology, Anichstrasse 35, Innsbruck, Austria.