Limits...
Ovarian dysgerminoma in two sisters.

Aldhafery BF - J Family Community Med (2008)

Bottom Line: Their exact etiology has not been determined.Few reports are found in the review of the literature on the incidence of dysgerminoma and other germ cell tumors in families.Some of these reports focus on the genetic abnormalities associated with germ cell tumor and the responsible gene.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.

ABSTRACT
Although rare, dysgerminomas are important irrespective of incidence because they affect women of reproductive age (i.e., <45 years). Dysgerminomas make up two thirds of all malignant ovarian neoplasms in women younger than 20 years. All dysgerminomas are considered malignant, but only one third of dysgerminomas behave aggressively. Their exact etiology has not been determined. Few reports are found in the review of the literature on the incidence of dysgerminoma and other germ cell tumors in families. Some of these reports focus on the genetic abnormalities associated with germ cell tumor and the responsible gene. Two cases of dysgerminomas diagnosed in two sisters aged 14 and 19 years old are presented here with their radiological studies.

No MeSH data available.


Related in: MedlinePlus

Patient One. Two consequent saggital proton density MRI of the pelvis showing a large mass arising from adnexa with upward extension into abdominal cavity. The mass appears of intermediate signal intensity with multiple internal foci of high signal intensity. Mass effect on adjacent structures such as the uterus, urinary bladder and rectum is seen.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3377126&req=5

Figure 1: Patient One. Two consequent saggital proton density MRI of the pelvis showing a large mass arising from adnexa with upward extension into abdominal cavity. The mass appears of intermediate signal intensity with multiple internal foci of high signal intensity. Mass effect on adjacent structures such as the uterus, urinary bladder and rectum is seen.

Mentions: Magnetic resonance imaging (MRI) of the pelvis (Figure 1) showed a large encapsulated mass arising from right adnexa with upward extension into abdominal cavity displacing and compressing both uterus and urinary bladder anteriorly and inferiorly. The mass was non-homogeneous with predominantly intermediate signal intensity in proton density images, and contained multiple cystic spaces representing previous tumor hemorrhage. No calcification or fatty component were identified. No enlarged lymph nodes were seen within the abdomen or pelvis. There was no invasion to adjacent structures.


Ovarian dysgerminoma in two sisters.

Aldhafery BF - J Family Community Med (2008)

Patient One. Two consequent saggital proton density MRI of the pelvis showing a large mass arising from adnexa with upward extension into abdominal cavity. The mass appears of intermediate signal intensity with multiple internal foci of high signal intensity. Mass effect on adjacent structures such as the uterus, urinary bladder and rectum is seen.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3377126&req=5

Figure 1: Patient One. Two consequent saggital proton density MRI of the pelvis showing a large mass arising from adnexa with upward extension into abdominal cavity. The mass appears of intermediate signal intensity with multiple internal foci of high signal intensity. Mass effect on adjacent structures such as the uterus, urinary bladder and rectum is seen.
Mentions: Magnetic resonance imaging (MRI) of the pelvis (Figure 1) showed a large encapsulated mass arising from right adnexa with upward extension into abdominal cavity displacing and compressing both uterus and urinary bladder anteriorly and inferiorly. The mass was non-homogeneous with predominantly intermediate signal intensity in proton density images, and contained multiple cystic spaces representing previous tumor hemorrhage. No calcification or fatty component were identified. No enlarged lymph nodes were seen within the abdomen or pelvis. There was no invasion to adjacent structures.

Bottom Line: Their exact etiology has not been determined.Few reports are found in the review of the literature on the incidence of dysgerminoma and other germ cell tumors in families.Some of these reports focus on the genetic abnormalities associated with germ cell tumor and the responsible gene.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.

ABSTRACT
Although rare, dysgerminomas are important irrespective of incidence because they affect women of reproductive age (i.e., <45 years). Dysgerminomas make up two thirds of all malignant ovarian neoplasms in women younger than 20 years. All dysgerminomas are considered malignant, but only one third of dysgerminomas behave aggressively. Their exact etiology has not been determined. Few reports are found in the review of the literature on the incidence of dysgerminoma and other germ cell tumors in families. Some of these reports focus on the genetic abnormalities associated with germ cell tumor and the responsible gene. Two cases of dysgerminomas diagnosed in two sisters aged 14 and 19 years old are presented here with their radiological studies.

No MeSH data available.


Related in: MedlinePlus