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Biopotency of Acalypha indica Linn on Membrane Bound ATPases and Marker Enzymes urolithic Rats.

Sathya M, Kokilavani R, Teepa KS, Balakrishnan A - Anc Sci Life (2011)

Bottom Line: There was a significant decrease in membrane bound enzymes such as Ca(2+) ATPase, Mg(2+) ATPase, Na(+)K(+) ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney.Therapeutic treatment with plant extract (200mg/kg b.wt.dose(-1) day(-1) oral(-1)) has significantly ameliorated to near normalcy in the curative group.These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore, India.

ABSTRACT
The ethanolic extract of Acalypha indica was tested for its biopotency on membrane bound enzymes and marker enzymes in urolithiasis in male wistar albino rats. Calcium oxalate urolithiasis was induced by 0.75% ethylene glycol in drinking water for 30 days. There was a significant decrease in membrane bound enzymes such as Ca(2+) ATPase, Mg(2+) ATPase, Na(+)K(+) ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney. The AST, ALT, ACP and ALP were increased in serum and urine of rats. Therapeutic treatment with plant extract (200mg/kg b.wt.dose(-1) day(-1) oral(-1)) has significantly ameliorated to near normalcy in the curative group. These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation.

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Related in: MedlinePlus

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d34e236: Experimental Design


Biopotency of Acalypha indica Linn on Membrane Bound ATPases and Marker Enzymes urolithic Rats.

Sathya M, Kokilavani R, Teepa KS, Balakrishnan A - Anc Sci Life (2011)

Experimental Design
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3377040&req=5

d34e236: Experimental Design
Bottom Line: There was a significant decrease in membrane bound enzymes such as Ca(2+) ATPase, Mg(2+) ATPase, Na(+)K(+) ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney.Therapeutic treatment with plant extract (200mg/kg b.wt.dose(-1) day(-1) oral(-1)) has significantly ameliorated to near normalcy in the curative group.These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore, India.

ABSTRACT
The ethanolic extract of Acalypha indica was tested for its biopotency on membrane bound enzymes and marker enzymes in urolithiasis in male wistar albino rats. Calcium oxalate urolithiasis was induced by 0.75% ethylene glycol in drinking water for 30 days. There was a significant decrease in membrane bound enzymes such as Ca(2+) ATPase, Mg(2+) ATPase, Na(+)K(+) ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney. The AST, ALT, ACP and ALP were increased in serum and urine of rats. Therapeutic treatment with plant extract (200mg/kg b.wt.dose(-1) day(-1) oral(-1)) has significantly ameliorated to near normalcy in the curative group. These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation.

No MeSH data available.


Related in: MedlinePlus