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Allgrove'S syndrome: case report and literature review.

Yasawy MI - J Family Community Med (2009)

Bottom Line: The results of these extensive investigations along with the clinical evaluations were consistent with Allgrove's syndrome.Glucocorticoid therapy was initiated.The management consisted of pneumatic cardiac dilatation and initiation of cortisone treatment.The patients' response was impressive and they resumed most of their usual activities.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, College of Medicine, King Faisal University, Dammam, Saudi Arabia.

ABSTRACT
This report concerns two brothers aged 10 and 18 years with long-standing dysphagia that started at age three and six years respectively. They had been diagnosed as achalasia and treated accordingly. The appearance of additional symptoms and clinical signs required further investigations including abdominal sonography, esophago-gastroduodenoscopy, barium swallow, esophageal manometry, computerized tomography (CT) of abdomen and brain, biochemical profiles, and neurologic and ophthalmic evaluations. The results of these extensive investigations along with the clinical evaluations were consistent with Allgrove's syndrome.Glucocorticoid therapy was initiated. The management consisted of pneumatic cardiac dilatation and initiation of cortisone treatment. The patients' response was impressive and they resumed most of their usual activities.

No MeSH data available.


Related in: MedlinePlus

Patient during follow-up in OPD
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Figure 2: Patient during follow-up in OPD

Mentions: His management included full supportive therapy that included hydration, nutrition, physiotherapy and artificial tears. The achalasia was managed by two sessions of pneumatic dilatations and he was kept on 10 mg prednisone/day as a maintenance dose. During one year of follow-up, he exhibited significant improvement and was able to eat well, walk without any support and he gained 25 kg weight i.e., his body mass index (BMI) increased from 13.3 to 21.3 (Figure 2).


Allgrove'S syndrome: case report and literature review.

Yasawy MI - J Family Community Med (2009)

Patient during follow-up in OPD
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3377019&req=5

Figure 2: Patient during follow-up in OPD
Mentions: His management included full supportive therapy that included hydration, nutrition, physiotherapy and artificial tears. The achalasia was managed by two sessions of pneumatic dilatations and he was kept on 10 mg prednisone/day as a maintenance dose. During one year of follow-up, he exhibited significant improvement and was able to eat well, walk without any support and he gained 25 kg weight i.e., his body mass index (BMI) increased from 13.3 to 21.3 (Figure 2).

Bottom Line: The results of these extensive investigations along with the clinical evaluations were consistent with Allgrove's syndrome.Glucocorticoid therapy was initiated.The management consisted of pneumatic cardiac dilatation and initiation of cortisone treatment.The patients' response was impressive and they resumed most of their usual activities.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, College of Medicine, King Faisal University, Dammam, Saudi Arabia.

ABSTRACT
This report concerns two brothers aged 10 and 18 years with long-standing dysphagia that started at age three and six years respectively. They had been diagnosed as achalasia and treated accordingly. The appearance of additional symptoms and clinical signs required further investigations including abdominal sonography, esophago-gastroduodenoscopy, barium swallow, esophageal manometry, computerized tomography (CT) of abdomen and brain, biochemical profiles, and neurologic and ophthalmic evaluations. The results of these extensive investigations along with the clinical evaluations were consistent with Allgrove's syndrome.Glucocorticoid therapy was initiated. The management consisted of pneumatic cardiac dilatation and initiation of cortisone treatment. The patients' response was impressive and they resumed most of their usual activities.

No MeSH data available.


Related in: MedlinePlus