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Gastric metastasis from a primary renal leiomyosarcoma.

Yodonawa S, Ogawa I, Yoshida S, Ito H, Kato A, Kubokawa R, Tokoshima E, Shimoyamada H - Case Rep Gastroenterol (2012)

Bottom Line: A 73-year-old man visited our hospital suffering from general weakness and intermittent tarry stools.Endoscopy revealed two submucosal tumors in the stomach.These tumors were diagnosed histologically as leiomyosarcoma and distal gastrectomy was performed.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Ibaraki Seinan Medical Center Hospital, Sakai, Japan.

ABSTRACT
Primary leiomyosarcoma of the kidney is rare. Here we report a case of metastasis of this tumor to the stomach. A 73-year-old man visited our hospital suffering from general weakness and intermittent tarry stools. He had undergone right nephrectomy for renal leiomyosarcoma 2 years previously. There had been no local recurrence or distant metastasis in the 2-year follow-up period. Endoscopy revealed two submucosal tumors in the stomach. These tumors were diagnosed histologically as leiomyosarcoma and distal gastrectomy was performed. Subsequent histochemical staining confirmed the diagnosis of gastric metastasis from renal leiomyosarcoma. The patient died due to metastases to the liver and bone 9 months after the operation. To the best of our knowledge, this is the first report of gastric metastasis from primary renal leiomyosarcoma.

No MeSH data available.


Related in: MedlinePlus

a Macroscopic findings for the resected specimen. The tumor formed a circumscribed, solid, white mass at the lower pole of the right kidney. b Histopathologically, the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures per 10 high-power fields were noted (hematoxylin-eosin staining, ×200).
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Figure 1: a Macroscopic findings for the resected specimen. The tumor formed a circumscribed, solid, white mass at the lower pole of the right kidney. b Histopathologically, the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures per 10 high-power fields were noted (hematoxylin-eosin staining, ×200).

Mentions: A 73-year-old man had undergone right nephrectomy for treatment of a right renal tumor 2 years previously. Grossly, the specimen consisted of a tumor arising at the lower pole of the right kidney. The tumor measured 12 × 11 × 8 cm and the cut surface showed the mass to be circumscribed, solid and white (fig. 1a). Histology showed that the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures were noted per 10 high-power fields (fig. 1b). Immunostaining showed tumor cells with cytoplasm that was diffusely positive for smooth muscle actin (SMA). Based on these data, leiomyosarcoma arising from the lower pole of the right kidney was diagnosed. Gastric endoscopy before nephrectomy showed normal findings. No local recurrence or systemic metastasis was detected in the 2-year follow-up period.


Gastric metastasis from a primary renal leiomyosarcoma.

Yodonawa S, Ogawa I, Yoshida S, Ito H, Kato A, Kubokawa R, Tokoshima E, Shimoyamada H - Case Rep Gastroenterol (2012)

a Macroscopic findings for the resected specimen. The tumor formed a circumscribed, solid, white mass at the lower pole of the right kidney. b Histopathologically, the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures per 10 high-power fields were noted (hematoxylin-eosin staining, ×200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3376334&req=5

Figure 1: a Macroscopic findings for the resected specimen. The tumor formed a circumscribed, solid, white mass at the lower pole of the right kidney. b Histopathologically, the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures per 10 high-power fields were noted (hematoxylin-eosin staining, ×200).
Mentions: A 73-year-old man had undergone right nephrectomy for treatment of a right renal tumor 2 years previously. Grossly, the specimen consisted of a tumor arising at the lower pole of the right kidney. The tumor measured 12 × 11 × 8 cm and the cut surface showed the mass to be circumscribed, solid and white (fig. 1a). Histology showed that the tumor was composed of spindle cells arranged in interlacing fascicles, with elongated, hyperchromatic nuclei and eosinophilic cytoplasm. Two mitotic figures were noted per 10 high-power fields (fig. 1b). Immunostaining showed tumor cells with cytoplasm that was diffusely positive for smooth muscle actin (SMA). Based on these data, leiomyosarcoma arising from the lower pole of the right kidney was diagnosed. Gastric endoscopy before nephrectomy showed normal findings. No local recurrence or systemic metastasis was detected in the 2-year follow-up period.

Bottom Line: A 73-year-old man visited our hospital suffering from general weakness and intermittent tarry stools.Endoscopy revealed two submucosal tumors in the stomach.These tumors were diagnosed histologically as leiomyosarcoma and distal gastrectomy was performed.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Ibaraki Seinan Medical Center Hospital, Sakai, Japan.

ABSTRACT
Primary leiomyosarcoma of the kidney is rare. Here we report a case of metastasis of this tumor to the stomach. A 73-year-old man visited our hospital suffering from general weakness and intermittent tarry stools. He had undergone right nephrectomy for renal leiomyosarcoma 2 years previously. There had been no local recurrence or distant metastasis in the 2-year follow-up period. Endoscopy revealed two submucosal tumors in the stomach. These tumors were diagnosed histologically as leiomyosarcoma and distal gastrectomy was performed. Subsequent histochemical staining confirmed the diagnosis of gastric metastasis from renal leiomyosarcoma. The patient died due to metastases to the liver and bone 9 months after the operation. To the best of our knowledge, this is the first report of gastric metastasis from primary renal leiomyosarcoma.

No MeSH data available.


Related in: MedlinePlus