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Primary actinomycosis of the thigh - a rare soft tissue infection with review of literature.

Khandelwal R, Jain I, Punia S, Singh A, Yadav S, Sharma P, Singh S, Mohanty PC - JRSM Short Rep (2012)

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Affiliation: Department of Surgery, Vardhman Mahavir Medical College , Safdarjang Hospital, New Delhi , India.

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Primary actinomycosis is a rare soft tissue infection which requires a high degree of clinical suspicion to diagnose and it should be differentiated from other chronic conditions like tuberculosis... There was no history of any trauma or insect bite at the site of the lesion... Gram staining revealed Gram positive bacilli, but no organisms could be cultured... Histopathological examination confirmed the diagnosis of actinomycosis (Figure 2)... Actinomyces produces disease when it is introduced into tissues by trauma, surgery, or infection... In our case, there was no history of past trauma or surgery and the actinomycosis was primary in nature... Cutaneous actinomycosis manifesting with nodular lesions that tend to form fistulae needs to be differentiated clinically from other chronic inflammatory skin diseases, such as cutaneous tuberculosis, sporotrichosis, and nocardiosis... Crystalline penicillin is widely used in the management of such lesions, and other drugs such as ampicillin/amoxicillin, erythromycin, sulphonamides, streptomycin, chloramphenicol, other tetracyclines and rifampicin have also been used... Surgery is indicated for small lesions or those which do not respond to medical treatment... There is a role of prolonged course of antibiotics after surgery... None declared No funding obtained Written informed consent was obtained from the patient or next of kin Rohan Khandelwal RK, PCM: Operating surgeons and involved in manuscript preparation... IJ: Pathologist; reported the histo-pathology slides SP, AS, SY: Assisting surgeons and helped in manuscript preparation PS, SS: Helped in review of literature and management of the patient Jody Parker

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Postoperative picture after resection of the lesion and split skin thickness graft in place
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SHORTS-11-137F4: Postoperative picture after resection of the lesion and split skin thickness graft in place

Mentions: The patient was started on co-trimaxozole and cindamycin for a period of 1 month, after which the patient was taken up for surgical excision of the lesion followed by split skin grafting to cover the created defect (FigureĀ 4). During excision, the whole lesion along with the involved muscle was removed. Multiple sinus tracks were encountered during surgery.Figure 4


Primary actinomycosis of the thigh - a rare soft tissue infection with review of literature.

Khandelwal R, Jain I, Punia S, Singh A, Yadav S, Sharma P, Singh S, Mohanty PC - JRSM Short Rep (2012)

Postoperative picture after resection of the lesion and split skin thickness graft in place
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3375841&req=5

SHORTS-11-137F4: Postoperative picture after resection of the lesion and split skin thickness graft in place
Mentions: The patient was started on co-trimaxozole and cindamycin for a period of 1 month, after which the patient was taken up for surgical excision of the lesion followed by split skin grafting to cover the created defect (FigureĀ 4). During excision, the whole lesion along with the involved muscle was removed. Multiple sinus tracks were encountered during surgery.Figure 4

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Vardhman Mahavir Medical College , Safdarjang Hospital, New Delhi , India.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Primary actinomycosis is a rare soft tissue infection which requires a high degree of clinical suspicion to diagnose and it should be differentiated from other chronic conditions like tuberculosis... There was no history of any trauma or insect bite at the site of the lesion... Gram staining revealed Gram positive bacilli, but no organisms could be cultured... Histopathological examination confirmed the diagnosis of actinomycosis (Figure 2)... Actinomyces produces disease when it is introduced into tissues by trauma, surgery, or infection... In our case, there was no history of past trauma or surgery and the actinomycosis was primary in nature... Cutaneous actinomycosis manifesting with nodular lesions that tend to form fistulae needs to be differentiated clinically from other chronic inflammatory skin diseases, such as cutaneous tuberculosis, sporotrichosis, and nocardiosis... Crystalline penicillin is widely used in the management of such lesions, and other drugs such as ampicillin/amoxicillin, erythromycin, sulphonamides, streptomycin, chloramphenicol, other tetracyclines and rifampicin have also been used... Surgery is indicated for small lesions or those which do not respond to medical treatment... There is a role of prolonged course of antibiotics after surgery... None declared No funding obtained Written informed consent was obtained from the patient or next of kin Rohan Khandelwal RK, PCM: Operating surgeons and involved in manuscript preparation... IJ: Pathologist; reported the histo-pathology slides SP, AS, SY: Assisting surgeons and helped in manuscript preparation PS, SS: Helped in review of literature and management of the patient Jody Parker

No MeSH data available.