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Acute respiratory distress in patient with laryngeal schwannoma.

Mannarini L, Morbini P, Bertino G, Gatti O, Benazzo M - Case Rep Med (2012)

Bottom Line: In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress.Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter.After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.

ABSTRACT
Schwannoma is a neurogenic benign tumour arising from the proliferation of Schwann cells present in the peripheral nerve sheath of myelinated nerves. This proliferation can hypothetically appear in every anatomic region of the human body, but the nerve sheath tumors rarely occur within the larynx. In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress. Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter. The patient underwent tracheotomy and a single-step surgical excision treatment of the mass which was recognized as a schwannoma at pathological examination. Tracheotomy was closed 2 weeks postoperatively. After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.

No MeSH data available.


Related in: MedlinePlus

At microscopic examination, the tumor showed characteristic Antoni A and Antoni B areas.
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fig2: At microscopic examination, the tumor showed characteristic Antoni A and Antoni B areas.

Mentions: A second single-step surgical excision was then decided. The left false vocal cord was incised with a sickle knife, and a microflap was dissected; blunt dissection revealed an encapsulated, soft tissue mass. The tumor was completely excised. Macroscopically the surgical specimen consisted of a well encapsulated tan-coloured tumor mass, measuring 4 × 2 cm. At microscopic examination, the tumor showed densely cellular areas with sheets of spindle cell palisading around amorphous matrix (Antoni A pattern) and less cellular areas with spindle cells in myxoid stroma and disorganized distribution (Antoni B pattern) (Figure 2). Tumor cells were strongly immunoreactive for S100 protein. Cellular proliferation index evaluated with Ki67 antibody was <1%.


Acute respiratory distress in patient with laryngeal schwannoma.

Mannarini L, Morbini P, Bertino G, Gatti O, Benazzo M - Case Rep Med (2012)

At microscopic examination, the tumor showed characteristic Antoni A and Antoni B areas.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3369560&req=5

fig2: At microscopic examination, the tumor showed characteristic Antoni A and Antoni B areas.
Mentions: A second single-step surgical excision was then decided. The left false vocal cord was incised with a sickle knife, and a microflap was dissected; blunt dissection revealed an encapsulated, soft tissue mass. The tumor was completely excised. Macroscopically the surgical specimen consisted of a well encapsulated tan-coloured tumor mass, measuring 4 × 2 cm. At microscopic examination, the tumor showed densely cellular areas with sheets of spindle cell palisading around amorphous matrix (Antoni A pattern) and less cellular areas with spindle cells in myxoid stroma and disorganized distribution (Antoni B pattern) (Figure 2). Tumor cells were strongly immunoreactive for S100 protein. Cellular proliferation index evaluated with Ki67 antibody was <1%.

Bottom Line: In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress.Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter.After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.

ABSTRACT
Schwannoma is a neurogenic benign tumour arising from the proliferation of Schwann cells present in the peripheral nerve sheath of myelinated nerves. This proliferation can hypothetically appear in every anatomic region of the human body, but the nerve sheath tumors rarely occur within the larynx. In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress. Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter. The patient underwent tracheotomy and a single-step surgical excision treatment of the mass which was recognized as a schwannoma at pathological examination. Tracheotomy was closed 2 weeks postoperatively. After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.

No MeSH data available.


Related in: MedlinePlus