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Comparison of Mortality between Japanese Peritoneal Dialysis and Hemodialysis Patients: A 5-Year Multicenter Follow-Up Study.

Suzuki K, Konta T, Ichikawa K, Ikeda A, Niino H, Hoshikawa M, Takahashi T, Abiko H, Ito M, Masakane I, Matsunaga T, Kudo K, Sato H, Degawa N, Kubota I - Int J Nephrol (2012)

Bottom Line: There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation.Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank P = 0.719).The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2, Iida-Nishi, Yamagata, Yamagata 990-9585, Japan.

ABSTRACT
To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patients (average age, 64.9 years; men, 53.6%; diabetic patients, 22.9%; median duration of dialysis, 48 months in all patients) and followed them for 5 years. During the follow-up period, 27 PD patients (16 cardiovascular and 11 non-cardiovascular deaths) and 27 HD patients died (14 cardiovascular and 13 non-cardiovascular deaths). There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation. Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank P = 0.719). The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant. Multivariate Cox analysis showed that the independent predictors for death were age and serum albumin levels, but not the dialysis modality. This study showed that the overall mortality was not significantly different between PD and HD patients, which suggests that dialysis modality might not be an independent factor for survival in Japanese patients.

No MeSH data available.


Cardiovascular and noncardiovascular mortalities by dialysis modality. PD: peritoneal dialysis; HD: hemodialysis.
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Related In: Results  -  Collection


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fig2: Cardiovascular and noncardiovascular mortalities by dialysis modality. PD: peritoneal dialysis; HD: hemodialysis.

Mentions: Then, we examined the difference in cardiovascular and noncardiovascular mortalities between PD and HD patients. The proportion of cardiovascular deaths among total deaths was not significantly different between PD and HD (59.3% versus 51.2%, P = 0.584). The event-free curves of PD and HD patients were almost identical, and event-free rate at the end of 5 years was not significantly different in cardiovascular deaths (log-rank P = 0.511) and noncardiovascular deaths (log-rank P = 0.844) (Figure 2).


Comparison of Mortality between Japanese Peritoneal Dialysis and Hemodialysis Patients: A 5-Year Multicenter Follow-Up Study.

Suzuki K, Konta T, Ichikawa K, Ikeda A, Niino H, Hoshikawa M, Takahashi T, Abiko H, Ito M, Masakane I, Matsunaga T, Kudo K, Sato H, Degawa N, Kubota I - Int J Nephrol (2012)

Cardiovascular and noncardiovascular mortalities by dialysis modality. PD: peritoneal dialysis; HD: hemodialysis.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3369474&req=5

fig2: Cardiovascular and noncardiovascular mortalities by dialysis modality. PD: peritoneal dialysis; HD: hemodialysis.
Mentions: Then, we examined the difference in cardiovascular and noncardiovascular mortalities between PD and HD patients. The proportion of cardiovascular deaths among total deaths was not significantly different between PD and HD (59.3% versus 51.2%, P = 0.584). The event-free curves of PD and HD patients were almost identical, and event-free rate at the end of 5 years was not significantly different in cardiovascular deaths (log-rank P = 0.511) and noncardiovascular deaths (log-rank P = 0.844) (Figure 2).

Bottom Line: There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation.Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank P = 0.719).The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2, Iida-Nishi, Yamagata, Yamagata 990-9585, Japan.

ABSTRACT
To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patients (average age, 64.9 years; men, 53.6%; diabetic patients, 22.9%; median duration of dialysis, 48 months in all patients) and followed them for 5 years. During the follow-up period, 27 PD patients (16 cardiovascular and 11 non-cardiovascular deaths) and 27 HD patients died (14 cardiovascular and 13 non-cardiovascular deaths). There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation. Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank P = 0.719). The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant. Multivariate Cox analysis showed that the independent predictors for death were age and serum albumin levels, but not the dialysis modality. This study showed that the overall mortality was not significantly different between PD and HD patients, which suggests that dialysis modality might not be an independent factor for survival in Japanese patients.

No MeSH data available.