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Celiac disease and dermatologic manifestations: many skin clue to unfold gluten-sensitive enteropathy.

Caproni M, Bonciolini V, D'Errico A, Antiga E, Fabbri P - Gastroenterol Res Pract (2012)

Bottom Line: Cutaneous manifestations of intestinal diseases are increasingly reported both in the adult and in the children, and this association cannot longer be considered a simple random.Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous.The aim of this paper is to describe the skin diseases frequently associated with CD, distinguishing them from those which have a relationship probably just coincidental.

View Article: PubMed Central - PubMed

Affiliation: Division of Dermatology, Department of Medical and Surgical Critical Care, University of Florence, 50129 Florence, Italy.

ABSTRACT
Cutaneous manifestations of intestinal diseases are increasingly reported both in the adult and in the children, and this association cannot longer be considered a simple random. Besides the well-known association between celiac disease (CD) and dermatitis herpetiformis (DH), considered as the cutaneous manifestation of gluten-dependent enteropathy, is more frequently reported also the association with other mucocutaneous diseases. Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous. The knowledge about pathogenic, epidemiological, clinical, and diagnostic aspects of CD is increasing in recent years as well as those about DH, but some aspects still remain to be defined, in particular the possible pathogenetic mechanisms involved in the association between both CD and DH and CD and other immunological skin diseases. The aim of this paper is to describe the skin diseases frequently associated with CD, distinguishing them from those which have a relationship probably just coincidental.

No MeSH data available.


Related in: MedlinePlus

Erythematous, popular, and vesiculosus lesions in a patient with DH.
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Related In: Results  -  Collection


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fig1: Erythematous, popular, and vesiculosus lesions in a patient with DH.

Mentions: DH lesions show a typical polymorphism consisting of erythema, urticarial plaques, papules, grouped vesicles and blisters associated with intense itch and therefore followed by erosions, excoriations, and hyperpigmentation (Figure 1). In addition to the morphology, also the symmetrical distribution of the lesions on the extensor surfaces of the upper and lower extremities, elbows, knees, scalp, nuchal area, and buttocks is considered a hallmark of the disease. At times face and groins may be involved. DH is rarely observed in darker-skinned individuals [12, 13]; however, there were no significant clinical differences compared to those North European.


Celiac disease and dermatologic manifestations: many skin clue to unfold gluten-sensitive enteropathy.

Caproni M, Bonciolini V, D'Errico A, Antiga E, Fabbri P - Gastroenterol Res Pract (2012)

Erythematous, popular, and vesiculosus lesions in a patient with DH.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3369470&req=5

fig1: Erythematous, popular, and vesiculosus lesions in a patient with DH.
Mentions: DH lesions show a typical polymorphism consisting of erythema, urticarial plaques, papules, grouped vesicles and blisters associated with intense itch and therefore followed by erosions, excoriations, and hyperpigmentation (Figure 1). In addition to the morphology, also the symmetrical distribution of the lesions on the extensor surfaces of the upper and lower extremities, elbows, knees, scalp, nuchal area, and buttocks is considered a hallmark of the disease. At times face and groins may be involved. DH is rarely observed in darker-skinned individuals [12, 13]; however, there were no significant clinical differences compared to those North European.

Bottom Line: Cutaneous manifestations of intestinal diseases are increasingly reported both in the adult and in the children, and this association cannot longer be considered a simple random.Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous.The aim of this paper is to describe the skin diseases frequently associated with CD, distinguishing them from those which have a relationship probably just coincidental.

View Article: PubMed Central - PubMed

Affiliation: Division of Dermatology, Department of Medical and Surgical Critical Care, University of Florence, 50129 Florence, Italy.

ABSTRACT
Cutaneous manifestations of intestinal diseases are increasingly reported both in the adult and in the children, and this association cannot longer be considered a simple random. Besides the well-known association between celiac disease (CD) and dermatitis herpetiformis (DH), considered as the cutaneous manifestation of gluten-dependent enteropathy, is more frequently reported also the association with other mucocutaneous diseases. Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous. The knowledge about pathogenic, epidemiological, clinical, and diagnostic aspects of CD is increasing in recent years as well as those about DH, but some aspects still remain to be defined, in particular the possible pathogenetic mechanisms involved in the association between both CD and DH and CD and other immunological skin diseases. The aim of this paper is to describe the skin diseases frequently associated with CD, distinguishing them from those which have a relationship probably just coincidental.

No MeSH data available.


Related in: MedlinePlus