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Multiple retroperitoneal schwannomas mimicking adrenal tumors.

Oishi K, Itamoto T, Okimoto S, Nishisaka T - Case Rep Oncol (2012)

Bottom Line: An abdominal computed tomography (CT) scan showed 1 non-enhancing mass with a low-density area, 4.6 cm in diameter, in the left adrenal region and another non-enhancing mass with a low-density area, 2.9 cm in diameter, in the para-aortic region.The tumors were completely resected.If the tumor increases in size, complete resection should be performed for pathological diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Departments of Surgery and Hiroshima Prefectural Hospital, Hiroshima, Japan.

ABSTRACT
Schwannomas are benign tumors mostly arising from the head and neck. Retroperitoneal schwannomas are rare. Here we report the case of a 68-year-old woman with multiple retroperitoneal schwannomas. An abdominal computed tomography (CT) scan showed 1 non-enhancing mass with a low-density area, 4.6 cm in diameter, in the left adrenal region and another non-enhancing mass with a low-density area, 2.9 cm in diameter, in the para-aortic region. The patient had regularly undergone CT scans for malignant tumor screening in maintenance dialysis patients. Retrospectively, the 2 tumors had existed in the same regions in previous CT scans and had gradually increased in size. The tumors were completely resected. Pathological diagnosis of both tumors was schwannoma. When a CT scan shows a slowly growing retroperitoneal tumor with a low-density area, schwannoma should be considered. If the tumor increases in size, complete resection should be performed for pathological diagnosis.

No MeSH data available.


Related in: MedlinePlus

Gross features of the schwannomas. The cut surface of the tumor 4.8 cm in diameter from the left adrenal region showed yellow solid areas and cystic degeneration (a, c), and the cut surface of the other tumor (3.0 cm in diameter) from the para-aortic region showed the same features (b, d).
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Figure 2: Gross features of the schwannomas. The cut surface of the tumor 4.8 cm in diameter from the left adrenal region showed yellow solid areas and cystic degeneration (a, c), and the cut surface of the other tumor (3.0 cm in diameter) from the para-aortic region showed the same features (b, d).

Mentions: On gross examination, the tumor measuring 4.8 cm in diameter in the left adrenal region included yellow solid areas and cystic degeneration. The other tumor, 3.0 cm in diameter, in the para-aortic region included the same features (fig. 2). Microscopic examination revealed that both tumors were composed of spindle cells with blunt nuclei in a fascicular pattern. Other regions in both tumors were composed of hypocellular spindle cells in a loose myxoid matrix. In immunohistochemical examination, spindle cells reacted to S-100 but did not react to anti-smooth-muscle actin. These findings corresponded to multiple schwannomas (fig. 3).


Multiple retroperitoneal schwannomas mimicking adrenal tumors.

Oishi K, Itamoto T, Okimoto S, Nishisaka T - Case Rep Oncol (2012)

Gross features of the schwannomas. The cut surface of the tumor 4.8 cm in diameter from the left adrenal region showed yellow solid areas and cystic degeneration (a, c), and the cut surface of the other tumor (3.0 cm in diameter) from the para-aortic region showed the same features (b, d).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3369249&req=5

Figure 2: Gross features of the schwannomas. The cut surface of the tumor 4.8 cm in diameter from the left adrenal region showed yellow solid areas and cystic degeneration (a, c), and the cut surface of the other tumor (3.0 cm in diameter) from the para-aortic region showed the same features (b, d).
Mentions: On gross examination, the tumor measuring 4.8 cm in diameter in the left adrenal region included yellow solid areas and cystic degeneration. The other tumor, 3.0 cm in diameter, in the para-aortic region included the same features (fig. 2). Microscopic examination revealed that both tumors were composed of spindle cells with blunt nuclei in a fascicular pattern. Other regions in both tumors were composed of hypocellular spindle cells in a loose myxoid matrix. In immunohistochemical examination, spindle cells reacted to S-100 but did not react to anti-smooth-muscle actin. These findings corresponded to multiple schwannomas (fig. 3).

Bottom Line: An abdominal computed tomography (CT) scan showed 1 non-enhancing mass with a low-density area, 4.6 cm in diameter, in the left adrenal region and another non-enhancing mass with a low-density area, 2.9 cm in diameter, in the para-aortic region.The tumors were completely resected.If the tumor increases in size, complete resection should be performed for pathological diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Departments of Surgery and Hiroshima Prefectural Hospital, Hiroshima, Japan.

ABSTRACT
Schwannomas are benign tumors mostly arising from the head and neck. Retroperitoneal schwannomas are rare. Here we report the case of a 68-year-old woman with multiple retroperitoneal schwannomas. An abdominal computed tomography (CT) scan showed 1 non-enhancing mass with a low-density area, 4.6 cm in diameter, in the left adrenal region and another non-enhancing mass with a low-density area, 2.9 cm in diameter, in the para-aortic region. The patient had regularly undergone CT scans for malignant tumor screening in maintenance dialysis patients. Retrospectively, the 2 tumors had existed in the same regions in previous CT scans and had gradually increased in size. The tumors were completely resected. Pathological diagnosis of both tumors was schwannoma. When a CT scan shows a slowly growing retroperitoneal tumor with a low-density area, schwannoma should be considered. If the tumor increases in size, complete resection should be performed for pathological diagnosis.

No MeSH data available.


Related in: MedlinePlus