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Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis.

Zhang H, Lv H, Huang PX, Lin Y, Hu XC, Liu P - Evid Based Complement Alternat Med (2012)

Bottom Line: There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 - 1.232TCMLDQ.The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF).Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shuguang Hospital-Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai 201203, China.

ABSTRACT
Objective. To compare and analyze the relevance and applied value of chronic liver disease questionnaire (CLDQ) and Traditional Chinese Medicine liver disease questionnaire (TCMLDQ) in patients with posthepatitic cirrhosis. Methods. The data of 146 patients' scales of CLDQ and TCMLDQ which based on the characteristics of chinese medical symptoms were collected. We made comparative analysis of the relationship between these two scales by the linear regression model and canonical correlation method and evaluated the advantages and disadvantages of two scales about its items setting and dimension definition. Result. There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 - 1.232TCMLDQ. The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF). Conclusion. These two scales have good consistency in the evaluation of severity and life quality of liver cirrhosis patients, so we suggested that TCMLDQ can be used to evaluate the severity and life quality of patients with posthepatitic cirrhosis.

No MeSH data available.


Related in: MedlinePlus

CLDQ total score, predicted values and individual 95% confidence intervals, and TCMLDQ total score line graph. Note: TCMLDQ: TCMLDQ actual measured total score; CLDQ: CLDQ actual measured total score; PRE: CLDQ scores predicted by TCMLDQ score; UICI: upper bounds of predicted CLDQ individual 95% confidence intervals; LICI: lower bounds of predicted CLDQ individual 95% confidence intervals.
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fig2: CLDQ total score, predicted values and individual 95% confidence intervals, and TCMLDQ total score line graph. Note: TCMLDQ: TCMLDQ actual measured total score; CLDQ: CLDQ actual measured total score; PRE: CLDQ scores predicted by TCMLDQ score; UICI: upper bounds of predicted CLDQ individual 95% confidence intervals; LICI: lower bounds of predicted CLDQ individual 95% confidence intervals.

Mentions: We predicted the total score of CLDQ with that of TCMLDQ. Individual 95% confidence intervals is a statistic which reflects the prediction effect of regression equation. It has lower and upper bounds (two predicted total scores of CLDQ) for the prediction interval of the CLDQ for every single case. Through the equation, we can estimate every patient's individual 95% confidence interval of CLDQ and verify whether the actual observation of CLDQ falls in its individual 95% confidence interval. The result has shown that 91.8% of patient's measured values of the CLDQ fall in their corresponding intervals, which means there is a good consistency between TCMLDQ and CLDQ (Figure 2).


Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis.

Zhang H, Lv H, Huang PX, Lin Y, Hu XC, Liu P - Evid Based Complement Alternat Med (2012)

CLDQ total score, predicted values and individual 95% confidence intervals, and TCMLDQ total score line graph. Note: TCMLDQ: TCMLDQ actual measured total score; CLDQ: CLDQ actual measured total score; PRE: CLDQ scores predicted by TCMLDQ score; UICI: upper bounds of predicted CLDQ individual 95% confidence intervals; LICI: lower bounds of predicted CLDQ individual 95% confidence intervals.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3369239&req=5

fig2: CLDQ total score, predicted values and individual 95% confidence intervals, and TCMLDQ total score line graph. Note: TCMLDQ: TCMLDQ actual measured total score; CLDQ: CLDQ actual measured total score; PRE: CLDQ scores predicted by TCMLDQ score; UICI: upper bounds of predicted CLDQ individual 95% confidence intervals; LICI: lower bounds of predicted CLDQ individual 95% confidence intervals.
Mentions: We predicted the total score of CLDQ with that of TCMLDQ. Individual 95% confidence intervals is a statistic which reflects the prediction effect of regression equation. It has lower and upper bounds (two predicted total scores of CLDQ) for the prediction interval of the CLDQ for every single case. Through the equation, we can estimate every patient's individual 95% confidence interval of CLDQ and verify whether the actual observation of CLDQ falls in its individual 95% confidence interval. The result has shown that 91.8% of patient's measured values of the CLDQ fall in their corresponding intervals, which means there is a good consistency between TCMLDQ and CLDQ (Figure 2).

Bottom Line: There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 - 1.232TCMLDQ.The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF).Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shuguang Hospital-Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai 201203, China.

ABSTRACT
Objective. To compare and analyze the relevance and applied value of chronic liver disease questionnaire (CLDQ) and Traditional Chinese Medicine liver disease questionnaire (TCMLDQ) in patients with posthepatitic cirrhosis. Methods. The data of 146 patients' scales of CLDQ and TCMLDQ which based on the characteristics of chinese medical symptoms were collected. We made comparative analysis of the relationship between these two scales by the linear regression model and canonical correlation method and evaluated the advantages and disadvantages of two scales about its items setting and dimension definition. Result. There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 - 1.232TCMLDQ. The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF). Conclusion. These two scales have good consistency in the evaluation of severity and life quality of liver cirrhosis patients, so we suggested that TCMLDQ can be used to evaluate the severity and life quality of patients with posthepatitic cirrhosis.

No MeSH data available.


Related in: MedlinePlus