Limits...
Comparison of retinal nerve fiber layer thickness measurements in healthy subjects using fourier and time domain optical coherence tomography.

Pinilla I, Garcia-Martin E, Idoipe M, Sancho E, Fuertes I - J Ophthalmol (2012)

Bottom Line: Average thickness and temporal quadrant showed significant differences using Cirrus and Stratus methods.Conclusions.Measurements obtained using Fourier domain device show better reproducibility.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Lozano Blesa University Hospital, c/ San Juan Bosco 15, 50009 Zaragoza, Spain.

ABSTRACT
Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain measurements in healthy subjects. Methods. One hundred and thirty-two eyes of 132 healthy subjects were scaned on the same day with both instruments, separated by 10 minutes from each other. Thickness of quadrant, average and the 12 different areas around the optic nerve were compared between Cirrus and Stratus. Repeatability, intraclass correlation coefficients (ICCs), and coefficients of variation (COVs) were calculated in RNFL measurements provided by Fourier domain device. Results. The average thickness in the optic cube was 95.50 μm using Cirrus and 97.85 μm using Stratus. Average thickness and temporal quadrant showed significant differences using Cirrus and Stratus methods. Reproducibility was better with Fourier domain OCT (mean COV of 4.54%) than with Stratus time-domain OCT (mean COV of 5.57%). Conclusions. Both scan options give reproducible RNFL thickness measurement, but there are differences between them. Measurements obtained using Fourier domain device show better reproducibility.

No MeSH data available.


Related in: MedlinePlus

Bland-Altman plots of the agreement in retinal nerve fiber layer (RNFL) thickness between Stratus OCT and Cirrus HD OCT. The difference (Stratus OCT average RNFL thickness minus Cirrus HD OCT average RNFL thickness) was plotted against the average of the three measurements for the average RNFL thickness Cirrus HD OCT measurements. SD: standard deviation.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3368551&req=5

fig4: Bland-Altman plots of the agreement in retinal nerve fiber layer (RNFL) thickness between Stratus OCT and Cirrus HD OCT. The difference (Stratus OCT average RNFL thickness minus Cirrus HD OCT average RNFL thickness) was plotted against the average of the three measurements for the average RNFL thickness Cirrus HD OCT measurements. SD: standard deviation.

Mentions: In most of the cases, direct comparison of RNFL measurements on the same eyes using both OCT instruments showed that the Stratus OCT gave a thinner measurement of the RNFL. As it would be expected, there was high correlation between measurements taken by both devices, and when differences between measurements were evaluated using Bland-Altman plots, considerable discrepancy between the two instruments was observed (Figure 4). Some authors have designed a correction factor to predict the RNFL measurement using other OCT devices, but this analysis is only an approximation.


Comparison of retinal nerve fiber layer thickness measurements in healthy subjects using fourier and time domain optical coherence tomography.

Pinilla I, Garcia-Martin E, Idoipe M, Sancho E, Fuertes I - J Ophthalmol (2012)

Bland-Altman plots of the agreement in retinal nerve fiber layer (RNFL) thickness between Stratus OCT and Cirrus HD OCT. The difference (Stratus OCT average RNFL thickness minus Cirrus HD OCT average RNFL thickness) was plotted against the average of the three measurements for the average RNFL thickness Cirrus HD OCT measurements. SD: standard deviation.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3368551&req=5

fig4: Bland-Altman plots of the agreement in retinal nerve fiber layer (RNFL) thickness between Stratus OCT and Cirrus HD OCT. The difference (Stratus OCT average RNFL thickness minus Cirrus HD OCT average RNFL thickness) was plotted against the average of the three measurements for the average RNFL thickness Cirrus HD OCT measurements. SD: standard deviation.
Mentions: In most of the cases, direct comparison of RNFL measurements on the same eyes using both OCT instruments showed that the Stratus OCT gave a thinner measurement of the RNFL. As it would be expected, there was high correlation between measurements taken by both devices, and when differences between measurements were evaluated using Bland-Altman plots, considerable discrepancy between the two instruments was observed (Figure 4). Some authors have designed a correction factor to predict the RNFL measurement using other OCT devices, but this analysis is only an approximation.

Bottom Line: Average thickness and temporal quadrant showed significant differences using Cirrus and Stratus methods.Conclusions.Measurements obtained using Fourier domain device show better reproducibility.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Lozano Blesa University Hospital, c/ San Juan Bosco 15, 50009 Zaragoza, Spain.

ABSTRACT
Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain measurements in healthy subjects. Methods. One hundred and thirty-two eyes of 132 healthy subjects were scaned on the same day with both instruments, separated by 10 minutes from each other. Thickness of quadrant, average and the 12 different areas around the optic nerve were compared between Cirrus and Stratus. Repeatability, intraclass correlation coefficients (ICCs), and coefficients of variation (COVs) were calculated in RNFL measurements provided by Fourier domain device. Results. The average thickness in the optic cube was 95.50 μm using Cirrus and 97.85 μm using Stratus. Average thickness and temporal quadrant showed significant differences using Cirrus and Stratus methods. Reproducibility was better with Fourier domain OCT (mean COV of 4.54%) than with Stratus time-domain OCT (mean COV of 5.57%). Conclusions. Both scan options give reproducible RNFL thickness measurement, but there are differences between them. Measurements obtained using Fourier domain device show better reproducibility.

No MeSH data available.


Related in: MedlinePlus