Limits...
Primary follicular lymphoma of the duodenum with erosions as atypical macroscopic features.

Takeuchi K, Iwamuro M, Imagawa A, Kubota Y, Miyatani K, Takata K, Okada H - Case Rep Med (2012)

Bottom Line: A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa.Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis.This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, Japan.

ABSTRACT
A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis. This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.

No MeSH data available.


Related in: MedlinePlus

Typical endoscopic image of follicular lymphoma of the duodenum observed in another patient (a 60-year-old man). Small whitish polypoid nodules were seen. In this patient, the entire gastrointestinal tract was evaluated by esophagogastroduodenoscopy, colonoscopy, and video capsule endoscopy. No involvement of other gastrointestinal tract was detected.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3368354&req=5

fig5: Typical endoscopic image of follicular lymphoma of the duodenum observed in another patient (a 60-year-old man). Small whitish polypoid nodules were seen. In this patient, the entire gastrointestinal tract was evaluated by esophagogastroduodenoscopy, colonoscopy, and video capsule endoscopy. No involvement of other gastrointestinal tract was detected.

Mentions: Yamamoto et al. summarized the cases with gastrointestinal follicular lymphoma reported in the English-language literature, and they noted that, among 133 cases with duodenal follicular lymphoma, multiple nodular lesions were found in 119 (89%) cases, mass lesions with or without ulcer in 5 (4%), polyps in 6 (5%), and other macroscopic features in 3 (2%) [5]. Recently, Takata et al. have reported 125 Japanese patients with primary gastrointestinal follicular lymphoma [2]. In their report, the macroscopic features of 110 patients were subcategorized as multiple nodules in 88 (80%), polyps in 13 (12%), ulcers in 5 (5%), diffuse disease in 2 (2%), and unclassified findings in 2 (2%). Therefore, multiple nodules were the predominant endoscopic feature (Figure 5), accounting for 80–89% of patients with gastrointestinal follicular lymphoma, and erosions as described in the presented case are considered to be rare.


Primary follicular lymphoma of the duodenum with erosions as atypical macroscopic features.

Takeuchi K, Iwamuro M, Imagawa A, Kubota Y, Miyatani K, Takata K, Okada H - Case Rep Med (2012)

Typical endoscopic image of follicular lymphoma of the duodenum observed in another patient (a 60-year-old man). Small whitish polypoid nodules were seen. In this patient, the entire gastrointestinal tract was evaluated by esophagogastroduodenoscopy, colonoscopy, and video capsule endoscopy. No involvement of other gastrointestinal tract was detected.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3368354&req=5

fig5: Typical endoscopic image of follicular lymphoma of the duodenum observed in another patient (a 60-year-old man). Small whitish polypoid nodules were seen. In this patient, the entire gastrointestinal tract was evaluated by esophagogastroduodenoscopy, colonoscopy, and video capsule endoscopy. No involvement of other gastrointestinal tract was detected.
Mentions: Yamamoto et al. summarized the cases with gastrointestinal follicular lymphoma reported in the English-language literature, and they noted that, among 133 cases with duodenal follicular lymphoma, multiple nodular lesions were found in 119 (89%) cases, mass lesions with or without ulcer in 5 (4%), polyps in 6 (5%), and other macroscopic features in 3 (2%) [5]. Recently, Takata et al. have reported 125 Japanese patients with primary gastrointestinal follicular lymphoma [2]. In their report, the macroscopic features of 110 patients were subcategorized as multiple nodules in 88 (80%), polyps in 13 (12%), ulcers in 5 (5%), diffuse disease in 2 (2%), and unclassified findings in 2 (2%). Therefore, multiple nodules were the predominant endoscopic feature (Figure 5), accounting for 80–89% of patients with gastrointestinal follicular lymphoma, and erosions as described in the presented case are considered to be rare.

Bottom Line: A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa.Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis.This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, Japan.

ABSTRACT
A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis. This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.

No MeSH data available.


Related in: MedlinePlus