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Setting up the speech production network: how oscillations contribute to lateralized information routing.

Gehrig J, Wibral M, Arnold C, Kell CA - Front Psychol (2012)

Bottom Line: This MEG study focuses on the spectro-temporal dynamics that contribute to the setup of this network.While a broadband low frequency effect was found for any task preparation in bilateral prefrontal cortices, preparation for overt speech production was specifically associated with left-lateralized alpha and beta suppression in temporal cortices and beta suppression in motor-related brain regions.Beta phase coupling in the entire speech production network was modulated by anticipation of overt reading.

View Article: PubMed Central - PubMed

Affiliation: Cognitive Neuroscience Group, Department of Neurology, Brain Imaging Center, Goethe University Frankfurt, Germany.

ABSTRACT
Speech production involves widely distributed brain regions. This MEG study focuses on the spectro-temporal dynamics that contribute to the setup of this network. In 21 participants performing a cue-target reading paradigm, we analyzed local oscillations during preparation for overt and covert reading in the time-frequency domain and localized sources using beamforming. Network dynamics were studied by comparing different dynamic causal models of beta phase coupling in and between hemispheres. While a broadband low frequency effect was found for any task preparation in bilateral prefrontal cortices, preparation for overt speech production was specifically associated with left-lateralized alpha and beta suppression in temporal cortices and beta suppression in motor-related brain regions. Beta phase coupling in the entire speech production network was modulated by anticipation of overt reading. We propose that the processes underlying the setup of the speech production network connect relevant brain regions by means of beta synchronization and prepare the network for left-lateralized information routing by suppression of inhibitory alpha and beta oscillations.

No MeSH data available.


Related in: MedlinePlus

Random effects Bayesian model selection of (A) models with unidirectional [top-down (td), bottom-up (bu)] and bidirectional (bi) coupling and (B) models comparing different interhemispheric coupling (for abbreviations please see text) and (C) models with different modulatory task effects [no modulation by task (no), modulation of top-down and bottom-up coupling (all)].
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Figure 8: Random effects Bayesian model selection of (A) models with unidirectional [top-down (td), bottom-up (bu)] and bidirectional (bi) coupling and (B) models comparing different interhemispheric coupling (for abbreviations please see text) and (C) models with different modulatory task effects [no modulation by task (no), modulation of top-down and bottom-up coupling (all)].

Mentions: Comparison of master-slave models against models with bidirectional coupling revealed that the speech production network is bidirectionally coupled in beta phase within hemispheres (Figure 8A). Assuming bidirectional coupling between hemispheres, the model with coupling between the SMA and bilateral dPMC, but no other interhemispheric coupling, was selected by Bayesian model comparison (Figure 8B). In all network connections, beta phase coupling was modulated by preparation for overt reading (Figure 8C).


Setting up the speech production network: how oscillations contribute to lateralized information routing.

Gehrig J, Wibral M, Arnold C, Kell CA - Front Psychol (2012)

Random effects Bayesian model selection of (A) models with unidirectional [top-down (td), bottom-up (bu)] and bidirectional (bi) coupling and (B) models comparing different interhemispheric coupling (for abbreviations please see text) and (C) models with different modulatory task effects [no modulation by task (no), modulation of top-down and bottom-up coupling (all)].
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3368321&req=5

Figure 8: Random effects Bayesian model selection of (A) models with unidirectional [top-down (td), bottom-up (bu)] and bidirectional (bi) coupling and (B) models comparing different interhemispheric coupling (for abbreviations please see text) and (C) models with different modulatory task effects [no modulation by task (no), modulation of top-down and bottom-up coupling (all)].
Mentions: Comparison of master-slave models against models with bidirectional coupling revealed that the speech production network is bidirectionally coupled in beta phase within hemispheres (Figure 8A). Assuming bidirectional coupling between hemispheres, the model with coupling between the SMA and bilateral dPMC, but no other interhemispheric coupling, was selected by Bayesian model comparison (Figure 8B). In all network connections, beta phase coupling was modulated by preparation for overt reading (Figure 8C).

Bottom Line: This MEG study focuses on the spectro-temporal dynamics that contribute to the setup of this network.While a broadband low frequency effect was found for any task preparation in bilateral prefrontal cortices, preparation for overt speech production was specifically associated with left-lateralized alpha and beta suppression in temporal cortices and beta suppression in motor-related brain regions.Beta phase coupling in the entire speech production network was modulated by anticipation of overt reading.

View Article: PubMed Central - PubMed

Affiliation: Cognitive Neuroscience Group, Department of Neurology, Brain Imaging Center, Goethe University Frankfurt, Germany.

ABSTRACT
Speech production involves widely distributed brain regions. This MEG study focuses on the spectro-temporal dynamics that contribute to the setup of this network. In 21 participants performing a cue-target reading paradigm, we analyzed local oscillations during preparation for overt and covert reading in the time-frequency domain and localized sources using beamforming. Network dynamics were studied by comparing different dynamic causal models of beta phase coupling in and between hemispheres. While a broadband low frequency effect was found for any task preparation in bilateral prefrontal cortices, preparation for overt speech production was specifically associated with left-lateralized alpha and beta suppression in temporal cortices and beta suppression in motor-related brain regions. Beta phase coupling in the entire speech production network was modulated by anticipation of overt reading. We propose that the processes underlying the setup of the speech production network connect relevant brain regions by means of beta synchronization and prepare the network for left-lateralized information routing by suppression of inhibitory alpha and beta oscillations.

No MeSH data available.


Related in: MedlinePlus