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Imaging beyond the ballistic limit in coherence imaging using multiply scattered light.

Giacomelli MG, Wax A - Opt Express (2011)

Bottom Line: We present an imaging system based on low coherence interferometric detection of multiply scattered light for extended depth imaging into highly scattering media.By incorporating angle-resolved detection, coherence imaging with multiply scattered photons is shown to be both feasible and potentially superior to existing techniques for performing time-resolved measurements of scattered light.The resolution and imaging contrast are compared to those obtained with conventional OCT systems which chiefly detect singly scattered light.

View Article: PubMed Central - PubMed

Affiliation: Department of Biomedical Engineering and Fitzpatrick Center for Photonics, Duke University, Durham, NC 27708, USA.

ABSTRACT
We present an imaging system based on low coherence interferometric detection of multiply scattered light for extended depth imaging into highly scattering media. By incorporating angle-resolved detection, coherence imaging with multiply scattered photons is shown to be both feasible and potentially superior to existing techniques for performing time-resolved measurements of scattered light. Imaging is demonstrated through nearly 100 mean free paths of scattering phantom in a single-ended geometry. The resolution and imaging contrast are compared to those obtained with conventional OCT systems which chiefly detect singly scattered light.

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Related in: MedlinePlus

Detected power relative to illumination power for both bead sizes as a function of mean free paths into the scattering media. Least squares fits to the attenuation verses mean free scattering events yield attenuation coefficients for multiply scattered photons of −1.05 and −0.8 dB/mfp for 1 and 11 μm microspheres respectively, significantly less than the 4.34 dB/mfp for ballistic attenuation.
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g005: Detected power relative to illumination power for both bead sizes as a function of mean free paths into the scattering media. Least squares fits to the attenuation verses mean free scattering events yield attenuation coefficients for multiply scattered photons of −1.05 and −0.8 dB/mfp for 1 and 11 μm microspheres respectively, significantly less than the 4.34 dB/mfp for ballistic attenuation.

Mentions: Transport theory predicts that diffusely scattered photons are exponentially attenuated with increasing number of mean free paths traversed, but at a reduced rate compared to ballistic photons because the transport mean free path is longer than the ballistic mean free path. This effect was confirmed in Fig. 5Fig. 5


Imaging beyond the ballistic limit in coherence imaging using multiply scattered light.

Giacomelli MG, Wax A - Opt Express (2011)

Detected power relative to illumination power for both bead sizes as a function of mean free paths into the scattering media. Least squares fits to the attenuation verses mean free scattering events yield attenuation coefficients for multiply scattered photons of −1.05 and −0.8 dB/mfp for 1 and 11 μm microspheres respectively, significantly less than the 4.34 dB/mfp for ballistic attenuation.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3368313&req=5

g005: Detected power relative to illumination power for both bead sizes as a function of mean free paths into the scattering media. Least squares fits to the attenuation verses mean free scattering events yield attenuation coefficients for multiply scattered photons of −1.05 and −0.8 dB/mfp for 1 and 11 μm microspheres respectively, significantly less than the 4.34 dB/mfp for ballistic attenuation.
Mentions: Transport theory predicts that diffusely scattered photons are exponentially attenuated with increasing number of mean free paths traversed, but at a reduced rate compared to ballistic photons because the transport mean free path is longer than the ballistic mean free path. This effect was confirmed in Fig. 5Fig. 5

Bottom Line: We present an imaging system based on low coherence interferometric detection of multiply scattered light for extended depth imaging into highly scattering media.By incorporating angle-resolved detection, coherence imaging with multiply scattered photons is shown to be both feasible and potentially superior to existing techniques for performing time-resolved measurements of scattered light.The resolution and imaging contrast are compared to those obtained with conventional OCT systems which chiefly detect singly scattered light.

View Article: PubMed Central - PubMed

Affiliation: Department of Biomedical Engineering and Fitzpatrick Center for Photonics, Duke University, Durham, NC 27708, USA.

ABSTRACT
We present an imaging system based on low coherence interferometric detection of multiply scattered light for extended depth imaging into highly scattering media. By incorporating angle-resolved detection, coherence imaging with multiply scattered photons is shown to be both feasible and potentially superior to existing techniques for performing time-resolved measurements of scattered light. Imaging is demonstrated through nearly 100 mean free paths of scattering phantom in a single-ended geometry. The resolution and imaging contrast are compared to those obtained with conventional OCT systems which chiefly detect singly scattered light.

Show MeSH
Related in: MedlinePlus