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Contact focusing multimodal microprobes for ultraprecise laser tissue surgery.

Darafsheh A, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN - Opt Express (2011)

Bottom Line: Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing.The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue.Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics and Optical Science, Center for Optoelectronics and Optical Communications, University of North Carolina at Charlotte, NC 28223, USA.

ABSTRACT
Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a two-fold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

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Related in: MedlinePlus

Comparison of (a) efficiency (η) of coupling of incident power to the central focused beam and (b) peak intensity (If) of the focused beam for microprobes formed by single, three, and five spheres.
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g004: Comparison of (a) efficiency (η) of coupling of incident power to the central focused beam and (b) peak intensity (If) of the focused beam for microprobes formed by single, three, and five spheres.

Mentions: Power coupling efficiency to the central focused beam (η=Pf/Pi) was estimated by using a small circular detector with radius equal to FWHM. According to this procedure, we calculated first the entire intensity profile over a broad area using a square detector, and then we used a small circular detector with the radius equal to FWHM to determine Pf. The calculated dependence of η on n is presented in Fig. 4(a)Fig. 4


Contact focusing multimodal microprobes for ultraprecise laser tissue surgery.

Darafsheh A, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN - Opt Express (2011)

Comparison of (a) efficiency (η) of coupling of incident power to the central focused beam and (b) peak intensity (If) of the focused beam for microprobes formed by single, three, and five spheres.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3368307&req=5

g004: Comparison of (a) efficiency (η) of coupling of incident power to the central focused beam and (b) peak intensity (If) of the focused beam for microprobes formed by single, three, and five spheres.
Mentions: Power coupling efficiency to the central focused beam (η=Pf/Pi) was estimated by using a small circular detector with radius equal to FWHM. According to this procedure, we calculated first the entire intensity profile over a broad area using a square detector, and then we used a small circular detector with the radius equal to FWHM to determine Pf. The calculated dependence of η on n is presented in Fig. 4(a)Fig. 4

Bottom Line: Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing.The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue.Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics and Optical Science, Center for Optoelectronics and Optical Communications, University of North Carolina at Charlotte, NC 28223, USA.

ABSTRACT
Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a two-fold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

Show MeSH
Related in: MedlinePlus