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Contact focusing multimodal microprobes for ultraprecise laser tissue surgery.

Darafsheh A, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN - Opt Express (2011)

Bottom Line: Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing.The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue.Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics and Optical Science, Center for Optoelectronics and Optical Communications, University of North Carolina at Charlotte, NC 28223, USA.

ABSTRACT
Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a two-fold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

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(a) Ray tracing inside the three-sphere (n=1.7) focusing microprobe, (b) schematic of the surface of the fiber core with the rays starting at random points, (c) intensity profiles calculated for a single sphere with n=1.7 as a function of the fiber to sphere distance (d).
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g001: (a) Ray tracing inside the three-sphere (n=1.7) focusing microprobe, (b) schematic of the surface of the fiber core with the rays starting at random points, (c) intensity profiles calculated for a single sphere with n=1.7 as a function of the fiber to sphere distance (d).

Mentions: The aim of our modeling was to create a generic design based on standard optical components, rather than one specific to a single application. As illustrated in Fig. 1 (a)Fig. 1


Contact focusing multimodal microprobes for ultraprecise laser tissue surgery.

Darafsheh A, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN - Opt Express (2011)

(a) Ray tracing inside the three-sphere (n=1.7) focusing microprobe, (b) schematic of the surface of the fiber core with the rays starting at random points, (c) intensity profiles calculated for a single sphere with n=1.7 as a function of the fiber to sphere distance (d).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3368307&req=5

g001: (a) Ray tracing inside the three-sphere (n=1.7) focusing microprobe, (b) schematic of the surface of the fiber core with the rays starting at random points, (c) intensity profiles calculated for a single sphere with n=1.7 as a function of the fiber to sphere distance (d).
Mentions: The aim of our modeling was to create a generic design based on standard optical components, rather than one specific to a single application. As illustrated in Fig. 1 (a)Fig. 1

Bottom Line: Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing.The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue.Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics and Optical Science, Center for Optoelectronics and Optical Communications, University of North Carolina at Charlotte, NC 28223, USA.

ABSTRACT
Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a two-fold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

Show MeSH
Related in: MedlinePlus