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International Salmonella Typhimurium DT104 infections, 1992-2001.

Helms M, Ethelberg S, Mølbak K, DT104 Study Gro - Emerging Infect. Dis. (2005)

Bottom Line: Typhimurium was increasing.This survey implies that MDR S.Typhimurium constitutes an increasing public health problem in large parts of the world and emphasizes the importance of surveillance and control programs.

View Article: PubMed Central - PubMed

Affiliation: Statens Serum Institut, Copenhagen, Denmark. mhe@ssi.dk

ABSTRACT
The incidence of multidrug-resistant (MDR) Salmonella Typhimurium infections in humans, and in particular MDR definitive phage type 104 (DT104), has increased substantially in many countries in the last 2 decades, often associated with increased illness. To examine the magnitude of this problem, a survey was conducted among countries with available antimicrobial resistance or phage typing surveillance data. A total of 29, primarily industrialized, countries participated in the survey, which covered the years 1992-2001. Overall, the incidence of MDR S. Typhimurium and DT104 increased continuously during this period, although the problem affected primarily Europe and North America. The increase appeared to have peaked in the United Kingdom but not in other countries. Also, the incidence of quinolone-resistant S. Typhimurium was increasing. This survey implies that MDR S. Typhimurium constitutes an increasing public health problem in large parts of the world and emphasizes the importance of surveillance and control programs.

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Salmonella enterica serovar Typhimurium DT104 as percentage of all S. Typhimurium in 8 world regions, 1992–2001. Only countries that had data available for 2 or more 2-year periods are included: United Kingdom and Ireland: England and Wales, Scotland, Ireland; Scandinavia: Denmark, Finland, Norway, Sweden; Western Europe: Austria, Germany, and the Netherlands; Eastern Europe: Czech Republic and Hungary; Southern Europe: Spain and Israel; North America: Canada, United States; Eastern Asia: the Republic of Korea; Oceania: Australia and New Zealand.
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Figure 2: Salmonella enterica serovar Typhimurium DT104 as percentage of all S. Typhimurium in 8 world regions, 1992–2001. Only countries that had data available for 2 or more 2-year periods are included: United Kingdom and Ireland: England and Wales, Scotland, Ireland; Scandinavia: Denmark, Finland, Norway, Sweden; Western Europe: Austria, Germany, and the Netherlands; Eastern Europe: Czech Republic and Hungary; Southern Europe: Spain and Israel; North America: Canada, United States; Eastern Asia: the Republic of Korea; Oceania: Australia and New Zealand.

Mentions: The proportion of S. Typhimurium strains that were DT104 and the proportion thereof that were found to be MDR are shown for each country in Table 2. In general, the incidence and proportion of DT104 increased throughout the period. In 1992, 8.7% of S. Typhimurium isolates were DT104, but in 2001 this proportion had increased to 33%. Again, large regional differences occurred. In the United Kingdom, the incidence peaked in 1996 and then decreased. In most other European countries and North America, the relative numbers of DT104 strains had increased throughout the period. In Australia and New Zealand, few DT104 isolates (0.7%) were seen among S. Typhimurium in 2001. The proportion of S. Typhimurium strains that were DT104 is depicted in Figure 2 (the countries are aggregated into 8 regions).


International Salmonella Typhimurium DT104 infections, 1992-2001.

Helms M, Ethelberg S, Mølbak K, DT104 Study Gro - Emerging Infect. Dis. (2005)

Salmonella enterica serovar Typhimurium DT104 as percentage of all S. Typhimurium in 8 world regions, 1992–2001. Only countries that had data available for 2 or more 2-year periods are included: United Kingdom and Ireland: England and Wales, Scotland, Ireland; Scandinavia: Denmark, Finland, Norway, Sweden; Western Europe: Austria, Germany, and the Netherlands; Eastern Europe: Czech Republic and Hungary; Southern Europe: Spain and Israel; North America: Canada, United States; Eastern Asia: the Republic of Korea; Oceania: Australia and New Zealand.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3367607&req=5

Figure 2: Salmonella enterica serovar Typhimurium DT104 as percentage of all S. Typhimurium in 8 world regions, 1992–2001. Only countries that had data available for 2 or more 2-year periods are included: United Kingdom and Ireland: England and Wales, Scotland, Ireland; Scandinavia: Denmark, Finland, Norway, Sweden; Western Europe: Austria, Germany, and the Netherlands; Eastern Europe: Czech Republic and Hungary; Southern Europe: Spain and Israel; North America: Canada, United States; Eastern Asia: the Republic of Korea; Oceania: Australia and New Zealand.
Mentions: The proportion of S. Typhimurium strains that were DT104 and the proportion thereof that were found to be MDR are shown for each country in Table 2. In general, the incidence and proportion of DT104 increased throughout the period. In 1992, 8.7% of S. Typhimurium isolates were DT104, but in 2001 this proportion had increased to 33%. Again, large regional differences occurred. In the United Kingdom, the incidence peaked in 1996 and then decreased. In most other European countries and North America, the relative numbers of DT104 strains had increased throughout the period. In Australia and New Zealand, few DT104 isolates (0.7%) were seen among S. Typhimurium in 2001. The proportion of S. Typhimurium strains that were DT104 is depicted in Figure 2 (the countries are aggregated into 8 regions).

Bottom Line: Typhimurium was increasing.This survey implies that MDR S.Typhimurium constitutes an increasing public health problem in large parts of the world and emphasizes the importance of surveillance and control programs.

View Article: PubMed Central - PubMed

Affiliation: Statens Serum Institut, Copenhagen, Denmark. mhe@ssi.dk

ABSTRACT
The incidence of multidrug-resistant (MDR) Salmonella Typhimurium infections in humans, and in particular MDR definitive phage type 104 (DT104), has increased substantially in many countries in the last 2 decades, often associated with increased illness. To examine the magnitude of this problem, a survey was conducted among countries with available antimicrobial resistance or phage typing surveillance data. A total of 29, primarily industrialized, countries participated in the survey, which covered the years 1992-2001. Overall, the incidence of MDR S. Typhimurium and DT104 increased continuously during this period, although the problem affected primarily Europe and North America. The increase appeared to have peaked in the United Kingdom but not in other countries. Also, the incidence of quinolone-resistant S. Typhimurium was increasing. This survey implies that MDR S. Typhimurium constitutes an increasing public health problem in large parts of the world and emphasizes the importance of surveillance and control programs.

Show MeSH
Related in: MedlinePlus