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West Nile virus epidemic, northeast Ohio, 2002.

Mandalakas AM, Kippes C, Sedransk J, Kile JR, Garg A, McLeod J, Berry RL, Marfin AA - Emerging Infect. Dis. (2005)

Bottom Line: Serum samples and sociodemographic data were obtained from 1,209 Ohio residents.West Nile virus immunoglobulin M (IgM) and IgG antibodies were detected by enzyme-linked immunosorbent assay and confirmed.Children were 4.5 times more likely to become infected yet 110 times less likely to have neuroinvasive disease develop.

View Article: PubMed Central - PubMed

Affiliation: Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA. anna.mandalakas@case.edu

ABSTRACT
Serum samples and sociodemographic data were obtained from 1,209 Ohio residents. West Nile virus immunoglobulin M (IgM) and IgG antibodies were detected by enzyme-linked immunosorbent assay and confirmed. Children were 4.5 times more likely to become infected yet 110 times less likely to have neuroinvasive disease develop.

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Related in: MedlinePlus

Comparison of age-stratified seroprevalence rates (gray bars) to the age-stratified incidence of West Nile neuroinvasive disease (WNND) (black line). Seroprevalence rates were measured in the 2002 seroprevalence study. The incidence of WNND was based on cases reported through the local disease reporting system during the 2002 transmission season.
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Figure 1: Comparison of age-stratified seroprevalence rates (gray bars) to the age-stratified incidence of West Nile neuroinvasive disease (WNND) (black line). Seroprevalence rates were measured in the 2002 seroprevalence study. The incidence of WNND was based on cases reported through the local disease reporting system during the 2002 transmission season.

Mentions: Seroprevalence varied significantly between age groups (p<0.05) (Table 1). Based on reported WNND cases and age-stratified seroprevalence rates, we estimate that 1 case of WNND occurred per 4,167 infected children 5–17 years of age, per 154 infected adults 18–64 years of age, and per 38 infected persons >65 years of age (Figure). Strata-specific seroprevalence values ranged from 1.5% to 3.3% but were not statistically different (Table 1).


West Nile virus epidemic, northeast Ohio, 2002.

Mandalakas AM, Kippes C, Sedransk J, Kile JR, Garg A, McLeod J, Berry RL, Marfin AA - Emerging Infect. Dis. (2005)

Comparison of age-stratified seroprevalence rates (gray bars) to the age-stratified incidence of West Nile neuroinvasive disease (WNND) (black line). Seroprevalence rates were measured in the 2002 seroprevalence study. The incidence of WNND was based on cases reported through the local disease reporting system during the 2002 transmission season.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3367333&req=5

Figure 1: Comparison of age-stratified seroprevalence rates (gray bars) to the age-stratified incidence of West Nile neuroinvasive disease (WNND) (black line). Seroprevalence rates were measured in the 2002 seroprevalence study. The incidence of WNND was based on cases reported through the local disease reporting system during the 2002 transmission season.
Mentions: Seroprevalence varied significantly between age groups (p<0.05) (Table 1). Based on reported WNND cases and age-stratified seroprevalence rates, we estimate that 1 case of WNND occurred per 4,167 infected children 5–17 years of age, per 154 infected adults 18–64 years of age, and per 38 infected persons >65 years of age (Figure). Strata-specific seroprevalence values ranged from 1.5% to 3.3% but were not statistically different (Table 1).

Bottom Line: Serum samples and sociodemographic data were obtained from 1,209 Ohio residents.West Nile virus immunoglobulin M (IgM) and IgG antibodies were detected by enzyme-linked immunosorbent assay and confirmed.Children were 4.5 times more likely to become infected yet 110 times less likely to have neuroinvasive disease develop.

View Article: PubMed Central - PubMed

Affiliation: Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA. anna.mandalakas@case.edu

ABSTRACT
Serum samples and sociodemographic data were obtained from 1,209 Ohio residents. West Nile virus immunoglobulin M (IgM) and IgG antibodies were detected by enzyme-linked immunosorbent assay and confirmed. Children were 4.5 times more likely to become infected yet 110 times less likely to have neuroinvasive disease develop.

Show MeSH
Related in: MedlinePlus