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Endoscopic-ultrasound-guided fine-needle aspiration and the role of the cytopathologist in solid pancreatic lesion diagnosis.

Iqbal S, Friedel D, Gupta M, Ogden L, Stavropoulos SN - Patholog Res Int (2012)

Bottom Line: The final diagnosis is based upon the correlation of clinical, EUS, and cytologic features.A close interaction with the cytopathologist is required in improving the diagnostic yield.Day to day examples of different solid pancreatic lesions have been presented at the end.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Medicine, Winthrop-University Hospital, Mineola, NY 1150, USA.

ABSTRACT
Endoscopic ultrasound (EUS) is the most sensitive imaging modality for solid pancreatic lesions. The specificity, however, is low (about 75%). It can be increased to 100% with an accuracy of 95% by the addition of fine-needle aspiration (FNA). Cytopathology plays an important role. The final diagnosis is based upon the correlation of clinical, EUS, and cytologic features. A close interaction with the cytopathologist is required in improving the diagnostic yield. In this paper, we present an overview of the role of EUS-guided FNA and importance of close interaction with the cytopathologist. Day to day examples of different solid pancreatic lesions have been presented at the end.

No MeSH data available.


Related in: MedlinePlus

High-grade neuroendocrine carcinoma. (a) EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion. (b) Multiple solid liver lesions were also noted, consistent with metastases.
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fig12: High-grade neuroendocrine carcinoma. (a) EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion. (b) Multiple solid liver lesions were also noted, consistent with metastases.

Mentions: (4) High-grade neuroendocrine carcinoma: a 87-year-old gentleman status after Billroth II surgery and history of choledocholithiasis with multiple ERCP procedures in the past presented with a new onset of biliary obstruction. CT abdomen showed multiple liver lesions and retroperitoneal/portal lymphadenopathy suspicious for malignancy. EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion (Figure 12). Two FNAs passed were done via transgastric approach. The specimen was analyzed by onsite cytopathologist for adequate cellularity. Celiac lymphadenopathy and multiple liver lesions were also noted, consistent with metastases.


Endoscopic-ultrasound-guided fine-needle aspiration and the role of the cytopathologist in solid pancreatic lesion diagnosis.

Iqbal S, Friedel D, Gupta M, Ogden L, Stavropoulos SN - Patholog Res Int (2012)

High-grade neuroendocrine carcinoma. (a) EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion. (b) Multiple solid liver lesions were also noted, consistent with metastases.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3362237&req=5

fig12: High-grade neuroendocrine carcinoma. (a) EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion. (b) Multiple solid liver lesions were also noted, consistent with metastases.
Mentions: (4) High-grade neuroendocrine carcinoma: a 87-year-old gentleman status after Billroth II surgery and history of choledocholithiasis with multiple ERCP procedures in the past presented with a new onset of biliary obstruction. CT abdomen showed multiple liver lesions and retroperitoneal/portal lymphadenopathy suspicious for malignancy. EUS showed a 29 mm by 27 mm pancreatic body hypoechoic and homogenous solid lesion (Figure 12). Two FNAs passed were done via transgastric approach. The specimen was analyzed by onsite cytopathologist for adequate cellularity. Celiac lymphadenopathy and multiple liver lesions were also noted, consistent with metastases.

Bottom Line: The final diagnosis is based upon the correlation of clinical, EUS, and cytologic features.A close interaction with the cytopathologist is required in improving the diagnostic yield.Day to day examples of different solid pancreatic lesions have been presented at the end.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Medicine, Winthrop-University Hospital, Mineola, NY 1150, USA.

ABSTRACT
Endoscopic ultrasound (EUS) is the most sensitive imaging modality for solid pancreatic lesions. The specificity, however, is low (about 75%). It can be increased to 100% with an accuracy of 95% by the addition of fine-needle aspiration (FNA). Cytopathology plays an important role. The final diagnosis is based upon the correlation of clinical, EUS, and cytologic features. A close interaction with the cytopathologist is required in improving the diagnostic yield. In this paper, we present an overview of the role of EUS-guided FNA and importance of close interaction with the cytopathologist. Day to day examples of different solid pancreatic lesions have been presented at the end.

No MeSH data available.


Related in: MedlinePlus