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Guidelines for histopathological specimen examination and diagnostic reporting of primary bone tumours.

Mangham DC, Athanasou NA - Clin Sarcoma Res (2011)

Bottom Line: This review is intended to provide histopathologists with guidelines for clinical assessment, specimen handling and diagnostic reporting of benign and malignant primary bone tumours.This ensures that the information needed for planning appropriate treatment of these complex tumours is provided.Consistency in diagnostic evaluation with respect to both terminology and report content facilitates liaison at multidisciplinary bone tumour meetings and collaboration between cancer units and networks, as well as providing a common database for audit of the clinical, radiological and pathological aspects of bone tumours.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
This review is intended to provide histopathologists with guidelines for clinical assessment, specimen handling and diagnostic reporting of benign and malignant primary bone tumours. Information from radiology, surgical, oncology and other clinical colleagues involved in the diagnosis and treatment of primary bone tumours should be properly assessed before undertaking a structured approach to specimen handling and histological reporting. This ensures that the information needed for planning appropriate treatment of these complex tumours is provided. Consistency in diagnostic evaluation with respect to both terminology and report content facilitates liaison at multidisciplinary bone tumour meetings and collaboration between cancer units and networks, as well as providing a common database for audit of the clinical, radiological and pathological aspects of bone tumours.

No MeSH data available.


Related in: MedlinePlus

Photograph of a slab taken through a specimen of an osteosarcoma of the lower femur. This provides information on the nature and site of sampled tissue blocks, the location of the tumour, its relation to bone resection margins, and permits calculation of the extent of tumour necrosis.
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Figure 1: Photograph of a slab taken through a specimen of an osteosarcoma of the lower femur. This provides information on the nature and site of sampled tissue blocks, the location of the tumour, its relation to bone resection margins, and permits calculation of the extent of tumour necrosis.

Mentions: • Blocks of tumour: a slab of all of the tumour in bone should be blocked out and a photographic record kept of where the tissue blocks for histology have been taken (Figure 1).


Guidelines for histopathological specimen examination and diagnostic reporting of primary bone tumours.

Mangham DC, Athanasou NA - Clin Sarcoma Res (2011)

Photograph of a slab taken through a specimen of an osteosarcoma of the lower femur. This provides information on the nature and site of sampled tissue blocks, the location of the tumour, its relation to bone resection margins, and permits calculation of the extent of tumour necrosis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3351796&req=5

Figure 1: Photograph of a slab taken through a specimen of an osteosarcoma of the lower femur. This provides information on the nature and site of sampled tissue blocks, the location of the tumour, its relation to bone resection margins, and permits calculation of the extent of tumour necrosis.
Mentions: • Blocks of tumour: a slab of all of the tumour in bone should be blocked out and a photographic record kept of where the tissue blocks for histology have been taken (Figure 1).

Bottom Line: This review is intended to provide histopathologists with guidelines for clinical assessment, specimen handling and diagnostic reporting of benign and malignant primary bone tumours.This ensures that the information needed for planning appropriate treatment of these complex tumours is provided.Consistency in diagnostic evaluation with respect to both terminology and report content facilitates liaison at multidisciplinary bone tumour meetings and collaboration between cancer units and networks, as well as providing a common database for audit of the clinical, radiological and pathological aspects of bone tumours.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
This review is intended to provide histopathologists with guidelines for clinical assessment, specimen handling and diagnostic reporting of benign and malignant primary bone tumours. Information from radiology, surgical, oncology and other clinical colleagues involved in the diagnosis and treatment of primary bone tumours should be properly assessed before undertaking a structured approach to specimen handling and histological reporting. This ensures that the information needed for planning appropriate treatment of these complex tumours is provided. Consistency in diagnostic evaluation with respect to both terminology and report content facilitates liaison at multidisciplinary bone tumour meetings and collaboration between cancer units and networks, as well as providing a common database for audit of the clinical, radiological and pathological aspects of bone tumours.

No MeSH data available.


Related in: MedlinePlus