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Vaginal metastasis of a Ewing Sarcoma five years after resection of the primary tumor.

Vanel N, Vierling V, Kreshak J, Gambarotti M, Cocchi S, Tranfaglia C, Vanel D - Clin Sarcoma Res (2011)

Bottom Line: She remained disease-free for five years, until age 40.A vaginal polyp was then detected during a routine gynaecologic examination.It was removed and histopathology revealed metastatic Ewing sarcoma.

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ABSTRACT
A 35-year-old female presented with pain and swelling of the left wrist. A diagnosis of Ewing sarcoma was made and she underwent neoadjuvant chemotherapy and surgery. Macroscopic viable areas remained on the map of the surgical specimen; as such, she was classified as a poor responder and received high dose adjuvant chemotherapy. She remained disease-free for five years, until age 40. A vaginal polyp was then detected during a routine gynaecologic examination. It was removed and histopathology revealed metastatic Ewing sarcoma. To our knowledge, this is the first reported case of a vaginal metastasis of Ewing sarcoma.

No MeSH data available.


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The metastasis is made of homogeneous small round cells.
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Figure 4: The metastasis is made of homogeneous small round cells.

Mentions: Five years later, during a routine gynaecologic exam, a vaginal polyp was found and removed. Histology revealed a ES metastasis (Figure 4), as confirmed by the characteristic translocation t(11, 22).(Figure 5). The rest of the evaluation (CT and bone scintigraphy) was normal.


Vaginal metastasis of a Ewing Sarcoma five years after resection of the primary tumor.

Vanel N, Vierling V, Kreshak J, Gambarotti M, Cocchi S, Tranfaglia C, Vanel D - Clin Sarcoma Res (2011)

The metastasis is made of homogeneous small round cells.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3351751&req=5

Figure 4: The metastasis is made of homogeneous small round cells.
Mentions: Five years later, during a routine gynaecologic exam, a vaginal polyp was found and removed. Histology revealed a ES metastasis (Figure 4), as confirmed by the characteristic translocation t(11, 22).(Figure 5). The rest of the evaluation (CT and bone scintigraphy) was normal.

Bottom Line: She remained disease-free for five years, until age 40.A vaginal polyp was then detected during a routine gynaecologic examination.It was removed and histopathology revealed metastatic Ewing sarcoma.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
A 35-year-old female presented with pain and swelling of the left wrist. A diagnosis of Ewing sarcoma was made and she underwent neoadjuvant chemotherapy and surgery. Macroscopic viable areas remained on the map of the surgical specimen; as such, she was classified as a poor responder and received high dose adjuvant chemotherapy. She remained disease-free for five years, until age 40. A vaginal polyp was then detected during a routine gynaecologic examination. It was removed and histopathology revealed metastatic Ewing sarcoma. To our knowledge, this is the first reported case of a vaginal metastasis of Ewing sarcoma.

No MeSH data available.


Related in: MedlinePlus