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Clinical outcomes of laparoscopic surgery for advanced transverse and descending colon cancer: a single-center experience.

Yamamoto M, Okuda J, Tanaka K, Kondo K, Tanigawa N, Uchiyama K - Surg Endosc (2011)

Bottom Line: Short-term and oncologic long-term outcomes were recorded.However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group.The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively.

View Article: PubMed Central - PubMed

Affiliation: Departments of General and Gastroenterological Surgery, Osaka Medical College Hospital, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan.

ABSTRACT

Background: The role of laparoscopic surgery in management of transverse and descending colon cancer remains controversial. The aim of the present study is to investigate the short-term and oncologic long-term outcomes associated with laparoscopic surgery for transverse and descending colon cancer.

Methods: This cohort study analyzed 245 patients (stage II disease, n = 70; stage III disease, n = 63) who underwent resection of transverse and descending colon cancers, including 200 laparoscopic surgeries (LAC) and 45 conventional open surgeries (OC) from December 1996 to December 2010. Short-term and oncologic long-term outcomes were recorded.

Results: The operative time was longer in the LAC group than in the OC group. However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group. The 5-year overall and disease-free survival rates for patients with stage II were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively. The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively.

Conclusion: Use of laparoscopic surgery resulted in acceptable short-term and oncologic outcomes in patients with advanced transverse and descending colon cancer.

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Related in: MedlinePlus

Kaplan–Meier curves of patients with stage II disease undergoing laparoscopic surgery or conventional open surgery: A overall survival rate and B disease-free survival rate. There was no statistically significant difference in survival between the two groups
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Fig2: Kaplan–Meier curves of patients with stage II disease undergoing laparoscopic surgery or conventional open surgery: A overall survival rate and B disease-free survival rate. There was no statistically significant difference in survival between the two groups

Mentions: The 5-year overall and disease-free survival rates in patients with stage II disease were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively (Fig. 1A, B). The 5-year overall and disease-free survival rates in patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively (Fig. 2A, B). The number of recurrences did not differ significantly between the LAC group and the OC group (2 versus 0; p = 0.322) in patients with stage II disease or between the LAC group and the OC group (11 versus 7; p = 0.346) in patients with stage III disease. There was no port-site recurrence or wound recurrence in either group, and there was no significant difference in the site of recurrence when comparing the groups.Fig. 1


Clinical outcomes of laparoscopic surgery for advanced transverse and descending colon cancer: a single-center experience.

Yamamoto M, Okuda J, Tanaka K, Kondo K, Tanigawa N, Uchiyama K - Surg Endosc (2011)

Kaplan–Meier curves of patients with stage II disease undergoing laparoscopic surgery or conventional open surgery: A overall survival rate and B disease-free survival rate. There was no statistically significant difference in survival between the two groups
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3351590&req=5

Fig2: Kaplan–Meier curves of patients with stage II disease undergoing laparoscopic surgery or conventional open surgery: A overall survival rate and B disease-free survival rate. There was no statistically significant difference in survival between the two groups
Mentions: The 5-year overall and disease-free survival rates in patients with stage II disease were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively (Fig. 1A, B). The 5-year overall and disease-free survival rates in patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively (Fig. 2A, B). The number of recurrences did not differ significantly between the LAC group and the OC group (2 versus 0; p = 0.322) in patients with stage II disease or between the LAC group and the OC group (11 versus 7; p = 0.346) in patients with stage III disease. There was no port-site recurrence or wound recurrence in either group, and there was no significant difference in the site of recurrence when comparing the groups.Fig. 1

Bottom Line: Short-term and oncologic long-term outcomes were recorded.However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group.The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively.

View Article: PubMed Central - PubMed

Affiliation: Departments of General and Gastroenterological Surgery, Osaka Medical College Hospital, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan.

ABSTRACT

Background: The role of laparoscopic surgery in management of transverse and descending colon cancer remains controversial. The aim of the present study is to investigate the short-term and oncologic long-term outcomes associated with laparoscopic surgery for transverse and descending colon cancer.

Methods: This cohort study analyzed 245 patients (stage II disease, n = 70; stage III disease, n = 63) who underwent resection of transverse and descending colon cancers, including 200 laparoscopic surgeries (LAC) and 45 conventional open surgeries (OC) from December 1996 to December 2010. Short-term and oncologic long-term outcomes were recorded.

Results: The operative time was longer in the LAC group than in the OC group. However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group. The 5-year overall and disease-free survival rates for patients with stage II were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively. The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively.

Conclusion: Use of laparoscopic surgery resulted in acceptable short-term and oncologic outcomes in patients with advanced transverse and descending colon cancer.

Show MeSH
Related in: MedlinePlus