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Early detection of ovarian cancer with conventional and contrast-enhanced transvaginal sonography: recent advances and potential improvements.

Fleischer AC, Lyshchik A, Hirari M, Moore RD, Abramson RG, Fishman DA - J Oncol (2012)

Bottom Line: These include improved assessment of tumor morphology with transvaginal sonography (TVS), and detection and characterization of tumor neovascularity with transvaginal color Doppler sonography (TV-CDS) and contrast-enhanced transvaginal sonography (CE-TVS).This paper will discuss and illustrate these improvements and describe how they enhance detection of early-stage ovarian cancer.Our initial experience with parametric mapping of CE-TVS will also be mentioned.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology & Radiological Sciences, Vanderbilt University Medical Center, 37232 Nashville, TN, USA.

ABSTRACT
Recently, there have been several major technical advances in the sonographic diagnosis of ovarian cancer in its early stages. These include improved assessment of tumor morphology with transvaginal sonography (TVS), and detection and characterization of tumor neovascularity with transvaginal color Doppler sonography (TV-CDS) and contrast-enhanced transvaginal sonography (CE-TVS). This paper will discuss and illustrate these improvements and describe how they enhance detection of early-stage ovarian cancer. Our initial experience with parametric mapping of CE-TVS will also be mentioned.

No MeSH data available.


Related in: MedlinePlus

CE-TVS of a benign fibroma.
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Related In: Results  -  Collection


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fig5: CE-TVS of a benign fibroma.

Mentions: Both micro- and macroscopically, tumor neovascularity is characterized as vessels that demonstrate irregular caliber and branching. TV-CDS can only detect flow in relatively large vessels. Microvascular (i.e., capillary) tumor neovascularity can be depicted using microbubble contrast (Figures 4, 5, and 6). On dynamic CE-TVS malignant tumor neovascularity usually demonstrates a higher peak of contrast enhancement and prolonged contrast washout when compared to benign tumors [1, 9, 14, 15] (Figure 9).


Early detection of ovarian cancer with conventional and contrast-enhanced transvaginal sonography: recent advances and potential improvements.

Fleischer AC, Lyshchik A, Hirari M, Moore RD, Abramson RG, Fishman DA - J Oncol (2012)

CE-TVS of a benign fibroma.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3351123&req=5

fig5: CE-TVS of a benign fibroma.
Mentions: Both micro- and macroscopically, tumor neovascularity is characterized as vessels that demonstrate irregular caliber and branching. TV-CDS can only detect flow in relatively large vessels. Microvascular (i.e., capillary) tumor neovascularity can be depicted using microbubble contrast (Figures 4, 5, and 6). On dynamic CE-TVS malignant tumor neovascularity usually demonstrates a higher peak of contrast enhancement and prolonged contrast washout when compared to benign tumors [1, 9, 14, 15] (Figure 9).

Bottom Line: These include improved assessment of tumor morphology with transvaginal sonography (TVS), and detection and characterization of tumor neovascularity with transvaginal color Doppler sonography (TV-CDS) and contrast-enhanced transvaginal sonography (CE-TVS).This paper will discuss and illustrate these improvements and describe how they enhance detection of early-stage ovarian cancer.Our initial experience with parametric mapping of CE-TVS will also be mentioned.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology & Radiological Sciences, Vanderbilt University Medical Center, 37232 Nashville, TN, USA.

ABSTRACT
Recently, there have been several major technical advances in the sonographic diagnosis of ovarian cancer in its early stages. These include improved assessment of tumor morphology with transvaginal sonography (TVS), and detection and characterization of tumor neovascularity with transvaginal color Doppler sonography (TV-CDS) and contrast-enhanced transvaginal sonography (CE-TVS). This paper will discuss and illustrate these improvements and describe how they enhance detection of early-stage ovarian cancer. Our initial experience with parametric mapping of CE-TVS will also be mentioned.

No MeSH data available.


Related in: MedlinePlus