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Emergency management of hypertension in children.

Singh D, Akingbola O, Yosypiv I, El-Dahr S - Int J Nephrol (2012)

Bottom Line: Both hypertensive emergencies and urgencies are known to cause significant morbidity and mortality.In this paper, we discuss the etiology, pathogenesis, and management of hypertensive crisis in children.An extensive database search using keywords was done to obtain the information.

View Article: PubMed Central - PubMed

Affiliation: Division of Pediatric Critical Care, Department of Pediatrics, Tulane University Health Sciences Center, 1430 Tulane Avenue, SL-37, New Orleans, LA 70112, USA.

ABSTRACT
Systemic arterial hypertension in children has traditionally been thought to be secondary in origin. Increased incidence of risk factors like obesity, sedentary life-styles, and faulty dietary habits has led to increased prevalence of the primary arterial hypertension (PAH), particularly in adolescent age children. PAH has become a global epidemic worldwide imposing huge economic constraint on health care. Sudden acute increase in systolic and diastolic blood pressure can lead to hypertensive crisis. While it generally pertains to secondary hypertension, occurrence of hypertensive crisis in PAH is however rare in children. Hypertensive crisis has been further subclassified depending on presence or absence of end-organ damage into hypertensive emergency or urgency. Both hypertensive emergencies and urgencies are known to cause significant morbidity and mortality. Increasing awareness among the physicians, targeted at investigation of the pathophysiology of hypertension and its complications, better screening methods, generation, and implementation of novel treatment modalities will impact overall outcomes. In this paper, we discuss the etiology, pathogenesis, and management of hypertensive crisis in children. An extensive database search using keywords was done to obtain the information.

No MeSH data available.


Related in: MedlinePlus

Mechanism of hypertensive crisis.
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Related In: Results  -  Collection


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fig2: Mechanism of hypertensive crisis.

Mentions: In addition, genetic mutations and polymorphisms [48], and insulin resistance [49], and abnormalities involving the sodium transport mechanisms like Na+/H+ exchanger, Na+/K+/2Cl−cotransporter, Na+Cl− cotransporter, Na+/K+ATPase, and sodium-phosphate cotransporter [50, 51] have also been implicated in the pathogenesis of hypertension. A possible mechanism of hypertensive crisis is shown in Figure 2.


Emergency management of hypertension in children.

Singh D, Akingbola O, Yosypiv I, El-Dahr S - Int J Nephrol (2012)

Mechanism of hypertensive crisis.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3345222&req=5

fig2: Mechanism of hypertensive crisis.
Mentions: In addition, genetic mutations and polymorphisms [48], and insulin resistance [49], and abnormalities involving the sodium transport mechanisms like Na+/H+ exchanger, Na+/K+/2Cl−cotransporter, Na+Cl− cotransporter, Na+/K+ATPase, and sodium-phosphate cotransporter [50, 51] have also been implicated in the pathogenesis of hypertension. A possible mechanism of hypertensive crisis is shown in Figure 2.

Bottom Line: Both hypertensive emergencies and urgencies are known to cause significant morbidity and mortality.In this paper, we discuss the etiology, pathogenesis, and management of hypertensive crisis in children.An extensive database search using keywords was done to obtain the information.

View Article: PubMed Central - PubMed

Affiliation: Division of Pediatric Critical Care, Department of Pediatrics, Tulane University Health Sciences Center, 1430 Tulane Avenue, SL-37, New Orleans, LA 70112, USA.

ABSTRACT
Systemic arterial hypertension in children has traditionally been thought to be secondary in origin. Increased incidence of risk factors like obesity, sedentary life-styles, and faulty dietary habits has led to increased prevalence of the primary arterial hypertension (PAH), particularly in adolescent age children. PAH has become a global epidemic worldwide imposing huge economic constraint on health care. Sudden acute increase in systolic and diastolic blood pressure can lead to hypertensive crisis. While it generally pertains to secondary hypertension, occurrence of hypertensive crisis in PAH is however rare in children. Hypertensive crisis has been further subclassified depending on presence or absence of end-organ damage into hypertensive emergency or urgency. Both hypertensive emergencies and urgencies are known to cause significant morbidity and mortality. Increasing awareness among the physicians, targeted at investigation of the pathophysiology of hypertension and its complications, better screening methods, generation, and implementation of novel treatment modalities will impact overall outcomes. In this paper, we discuss the etiology, pathogenesis, and management of hypertensive crisis in children. An extensive database search using keywords was done to obtain the information.

No MeSH data available.


Related in: MedlinePlus