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Cardiovascular Complications in Ciguatera Fish Poisoning: A Wake-up Call.

Senthilkumaran S, Meenakshisundaram R, Michaels AD, Suresh P, Thirumalaikolundusubramanian P - Heart Views (2011)

Bottom Line: Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin.Ciguatoxin is a sodium channel agonist with cholinergic and adrenergic activity.Fatality and long-term sequelae are not uncommon with ciguatoxin poisoning and educating the general population is essential.

View Article: PubMed Central - PubMed

Affiliation: Department of Accident, Emergency and Critical Care Medicine, Sri Gokulam Hospitals and Research Institute, Salem, Tamil Nadu, India.

ABSTRACT
Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin. It causes a clinical syndrome that comprises classic gastrointestinal, neurological and cardiovascular symptoms. Ciguatoxin is a sodium channel agonist with cholinergic and adrenergic activity. Although cardiovascular symptoms are rare with ciguatoxin, we report two cases with bradycardia and hypotension. Fatality and long-term sequelae are not uncommon with ciguatoxin poisoning and educating the general population is essential.

No MeSH data available.


Related in: MedlinePlus

Electrocardiogram (EKG) of the patient 2
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Figure 2: Electrocardiogram (EKG) of the patient 2

Mentions: An 18-year-old healthy female, presented with complaints of dizziness, nausea, watery diarrhea, diffuse pruritis, circumoral tingling, and chest discomfort following consumption of mackerel fish. She was stable clinically with an unremarkable systemic examination. Her supine blood pressure was 80/40 mmHg with a heart rate of 42 beats per minute. The electrocardiogram showed sinus bradycardia at 42 beats per minute. She was treated in the same manner as the previous case. She required a total dose of 30 mgs of atropine over 48 hours for the correction of bradycardia. She was discharged on day four, and follow-up did not reveal any abnormality. EKG of the patient is shown in Figure 2. However, both the patients did not show any abnormality in QRS complex or QT interval.


Cardiovascular Complications in Ciguatera Fish Poisoning: A Wake-up Call.

Senthilkumaran S, Meenakshisundaram R, Michaels AD, Suresh P, Thirumalaikolundusubramanian P - Heart Views (2011)

Electrocardiogram (EKG) of the patient 2
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3345153&req=5

Figure 2: Electrocardiogram (EKG) of the patient 2
Mentions: An 18-year-old healthy female, presented with complaints of dizziness, nausea, watery diarrhea, diffuse pruritis, circumoral tingling, and chest discomfort following consumption of mackerel fish. She was stable clinically with an unremarkable systemic examination. Her supine blood pressure was 80/40 mmHg with a heart rate of 42 beats per minute. The electrocardiogram showed sinus bradycardia at 42 beats per minute. She was treated in the same manner as the previous case. She required a total dose of 30 mgs of atropine over 48 hours for the correction of bradycardia. She was discharged on day four, and follow-up did not reveal any abnormality. EKG of the patient is shown in Figure 2. However, both the patients did not show any abnormality in QRS complex or QT interval.

Bottom Line: Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin.Ciguatoxin is a sodium channel agonist with cholinergic and adrenergic activity.Fatality and long-term sequelae are not uncommon with ciguatoxin poisoning and educating the general population is essential.

View Article: PubMed Central - PubMed

Affiliation: Department of Accident, Emergency and Critical Care Medicine, Sri Gokulam Hospitals and Research Institute, Salem, Tamil Nadu, India.

ABSTRACT
Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin. It causes a clinical syndrome that comprises classic gastrointestinal, neurological and cardiovascular symptoms. Ciguatoxin is a sodium channel agonist with cholinergic and adrenergic activity. Although cardiovascular symptoms are rare with ciguatoxin, we report two cases with bradycardia and hypotension. Fatality and long-term sequelae are not uncommon with ciguatoxin poisoning and educating the general population is essential.

No MeSH data available.


Related in: MedlinePlus