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Tizoxanide pyridine monosolvate.

Zheng H, Deng H, Chen Y, Li D - Acta Crystallogr Sect E Struct Rep Online (2012)

Bottom Line: An intamolecular O-H⋯N hydrogen bond occurs in the tizoxanide.In the crystal, the components are linked by an O-H⋯N hydrogen bond, forming a zigzag chain along the c axis.Aromatic π-π inter-actions between inversion-related pyridine rings [centroid-centroid distance = 3.803 (6) Å] are also observed.

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Affiliation: School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, 510006, People's Republic of China.

ABSTRACT
IN THE TITLE COMPOUND [SYSTEMATIC NAME: 2-hy-droxy-N-(5-nitro-1,3-thia-zol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O-H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O-H⋯N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π-π inter-actions between inversion-related pyridine rings [centroid-centroid distance = 3.803 (6) Å] are also observed.

No MeSH data available.


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The thermogravimetric analysis of the title compound showing a one-step molecular weight loss of 22.43% corresponding to one pyridine molecule.
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Fap3: The thermogravimetric analysis of the title compound showing a one-step molecular weight loss of 22.43% corresponding to one pyridine molecule.


Tizoxanide pyridine monosolvate.

Zheng H, Deng H, Chen Y, Li D - Acta Crystallogr Sect E Struct Rep Online (2012)

The thermogravimetric analysis of the title compound showing a one-step molecular weight loss of 22.43% corresponding to one pyridine molecule.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3344569&req=5

Fap3: The thermogravimetric analysis of the title compound showing a one-step molecular weight loss of 22.43% corresponding to one pyridine molecule.
Bottom Line: An intamolecular O-H⋯N hydrogen bond occurs in the tizoxanide.In the crystal, the components are linked by an O-H⋯N hydrogen bond, forming a zigzag chain along the c axis.Aromatic π-π inter-actions between inversion-related pyridine rings [centroid-centroid distance = 3.803 (6) Å] are also observed.

View Article: PubMed Central - HTML - PubMed

Affiliation: School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, 510006, People's Republic of China.

ABSTRACT
IN THE TITLE COMPOUND [SYSTEMATIC NAME: 2-hy-droxy-N-(5-nitro-1,3-thia-zol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O-H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O-H⋯N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π-π inter-actions between inversion-related pyridine rings [centroid-centroid distance = 3.803 (6) Å] are also observed.

No MeSH data available.


Related in: MedlinePlus