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4-(4-Chloro-phen-yl)-2,6-bis-(1H-indol-3-yl)-1,4-dihydro-pyridine-3,5-dicarbo-nitrile ethanol monosolvate.

Zhu SL, Zheng JN - Acta Crystallogr Sect E Struct Rep Online (2012)

Bottom Line: An intra-molecular C-H⋯Cl hydrogen bond occurs.In the crystal, mol-ecules are linked by N-H⋯N, N-H⋯O and O-H⋯N hydrogen bonds into layers parallel to (001).There are short C-H⋯Cl contacts between mol-ecules in neighboring layers.

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Affiliation: Key Laboratory of Biological Cancer Therapy, Xuzhou Medical College, Xuzhou 221004, People's Republic of China.

ABSTRACT
In the title compound, C(29)H(18)ClN(5)·C(2)H(6)O, the dihydro-pyridine ring adopts a strongly flattened envelope conformation, with a maximum deviation of 0.139 (2) Å from its best plane for the Csp(3) atom. The dihedral angles between the dihydro-pyridine ring plane and the two indole rings in positions 2 and 6 are 34.28 (5) and 40.50 (6)°, respectively. In turn, the benzene ring and the dihydro-pyridine ring are oriented at a dihedral angle of 74.69 (6)°. An intra-molecular C-H⋯Cl hydrogen bond occurs. In the crystal, mol-ecules are linked by N-H⋯N, N-H⋯O and O-H⋯N hydrogen bonds into layers parallel to (001). There are short C-H⋯Cl contacts between mol-ecules in neighboring layers.

No MeSH data available.


A packing diagram of the title compound. Hydrogen bonds are shown as dashed lines.
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Fap2: A packing diagram of the title compound. Hydrogen bonds are shown as dashed lines.


4-(4-Chloro-phen-yl)-2,6-bis-(1H-indol-3-yl)-1,4-dihydro-pyridine-3,5-dicarbo-nitrile ethanol monosolvate.

Zhu SL, Zheng JN - Acta Crystallogr Sect E Struct Rep Online (2012)

A packing diagram of the title compound. Hydrogen bonds are shown as dashed lines.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3344446&req=5

Fap2: A packing diagram of the title compound. Hydrogen bonds are shown as dashed lines.
Bottom Line: An intra-molecular C-H⋯Cl hydrogen bond occurs.In the crystal, mol-ecules are linked by N-H⋯N, N-H⋯O and O-H⋯N hydrogen bonds into layers parallel to (001).There are short C-H⋯Cl contacts between mol-ecules in neighboring layers.

View Article: PubMed Central - HTML - PubMed

Affiliation: Key Laboratory of Biological Cancer Therapy, Xuzhou Medical College, Xuzhou 221004, People's Republic of China.

ABSTRACT
In the title compound, C(29)H(18)ClN(5)·C(2)H(6)O, the dihydro-pyridine ring adopts a strongly flattened envelope conformation, with a maximum deviation of 0.139 (2) Å from its best plane for the Csp(3) atom. The dihedral angles between the dihydro-pyridine ring plane and the two indole rings in positions 2 and 6 are 34.28 (5) and 40.50 (6)°, respectively. In turn, the benzene ring and the dihydro-pyridine ring are oriented at a dihedral angle of 74.69 (6)°. An intra-molecular C-H⋯Cl hydrogen bond occurs. In the crystal, mol-ecules are linked by N-H⋯N, N-H⋯O and O-H⋯N hydrogen bonds into layers parallel to (001). There are short C-H⋯Cl contacts between mol-ecules in neighboring layers.

No MeSH data available.