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Studies on strains of Streptococcus mutans isolated from caries-active and caries-free individuals in Iceland.

Holbrook WP, Magnúsdóttir MO - J Oral Microbiol (2012)

Bottom Line: Dental caries has been strongly associated with mutans streptococci, particularly Streptococcus mutans and S. sobrinus.The high levels of caries generally found in Iceland have enabled several studies to be performed on the variation within strains of S. mutans.Strains from individuals with active caries generally adhered better to apatite, were more vigorous in decalcifying apatite and had bacteriocin-like activity that was likely to help the strain compete successfully with other strains, for example in the dental plaque biofilm.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Odontology, University of Iceland, Reykjavík, Iceland.

ABSTRACT

Background: Dental caries has been strongly associated with mutans streptococci, particularly Streptococcus mutans and S. sobrinus. Many studies have linked these organisms to the carious process and counts of mutans streptococci have been used to monitor caries risk. The high levels of caries generally found in Iceland have enabled several studies to be performed on the variation within strains of S. mutans.

Methods: This paper reports some studies showing phenotypic differences between strains of S. mutans that were related to whether the strain was isolated from an individual with active caries or from a caries-free subject.

Results: Strains from individuals with active caries generally adhered better to apatite, were more vigorous in decalcifying apatite and had bacteriocin-like activity that was likely to help the strain compete successfully with other strains, for example in the dental plaque biofilm.

Conclusions: Phenotypic differences exist between strains of S. mutans depending on the caries activity of the individual from whom the strain was isolated.

No MeSH data available.


Related in: MedlinePlus

Pattern of bacteriocin-like activity within strains of S. mutans (strains 1–8 isolated from caries-free subjects and strains 9–16 from caries-active subjects). Note that the strains from caries-active subjects produce bacteriocins that inhibit growth of more indicator strains than do strains isolated from caries-free subjects.
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Figure 0001: Pattern of bacteriocin-like activity within strains of S. mutans (strains 1–8 isolated from caries-free subjects and strains 9–16 from caries-active subjects). Note that the strains from caries-active subjects produce bacteriocins that inhibit growth of more indicator strains than do strains isolated from caries-free subjects.

Mentions: Strains isolated from caries-active subjects showed greater bacteriocin-like activity against other isolates of S. mutans (average 3.4 strains) than did strains isolated from subjects that were caries free (average 1.0 strains; p<0.01(chi2); see Fig. 1). Furthermore 7/8 strains from caries active individuals inhibited ≥2 other strains of S. mutans whereas only 1/8 strains from a caries-free individual inhibited ≥2 other strains of S. mutans.


Studies on strains of Streptococcus mutans isolated from caries-active and caries-free individuals in Iceland.

Holbrook WP, Magnúsdóttir MO - J Oral Microbiol (2012)

Pattern of bacteriocin-like activity within strains of S. mutans (strains 1–8 isolated from caries-free subjects and strains 9–16 from caries-active subjects). Note that the strains from caries-active subjects produce bacteriocins that inhibit growth of more indicator strains than do strains isolated from caries-free subjects.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3316909&req=5

Figure 0001: Pattern of bacteriocin-like activity within strains of S. mutans (strains 1–8 isolated from caries-free subjects and strains 9–16 from caries-active subjects). Note that the strains from caries-active subjects produce bacteriocins that inhibit growth of more indicator strains than do strains isolated from caries-free subjects.
Mentions: Strains isolated from caries-active subjects showed greater bacteriocin-like activity against other isolates of S. mutans (average 3.4 strains) than did strains isolated from subjects that were caries free (average 1.0 strains; p<0.01(chi2); see Fig. 1). Furthermore 7/8 strains from caries active individuals inhibited ≥2 other strains of S. mutans whereas only 1/8 strains from a caries-free individual inhibited ≥2 other strains of S. mutans.

Bottom Line: Dental caries has been strongly associated with mutans streptococci, particularly Streptococcus mutans and S. sobrinus.The high levels of caries generally found in Iceland have enabled several studies to be performed on the variation within strains of S. mutans.Strains from individuals with active caries generally adhered better to apatite, were more vigorous in decalcifying apatite and had bacteriocin-like activity that was likely to help the strain compete successfully with other strains, for example in the dental plaque biofilm.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Odontology, University of Iceland, Reykjavík, Iceland.

ABSTRACT

Background: Dental caries has been strongly associated with mutans streptococci, particularly Streptococcus mutans and S. sobrinus. Many studies have linked these organisms to the carious process and counts of mutans streptococci have been used to monitor caries risk. The high levels of caries generally found in Iceland have enabled several studies to be performed on the variation within strains of S. mutans.

Methods: This paper reports some studies showing phenotypic differences between strains of S. mutans that were related to whether the strain was isolated from an individual with active caries or from a caries-free subject.

Results: Strains from individuals with active caries generally adhered better to apatite, were more vigorous in decalcifying apatite and had bacteriocin-like activity that was likely to help the strain compete successfully with other strains, for example in the dental plaque biofilm.

Conclusions: Phenotypic differences exist between strains of S. mutans depending on the caries activity of the individual from whom the strain was isolated.

No MeSH data available.


Related in: MedlinePlus