Limits...
Salivary pH as a marker of plasma adiponectin concentrations in Women.

Tremblay M, Loucif Y, Methot J, Brisson D, Gaudet D - Diabetol Metab Syndr (2012)

Bottom Line: Plasma adiponectin levels progressively increased across salivary pH quartiles (p = 0.005).These results suggest that salivary pH is a significant correlate of plasma adiponectin levels in women.Salivary pH, a simple, inexpensive and non-invasive measure, could be a very promising avenue.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Medicine, Université de Montréal, ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, QC, Canada. daniel.gaudet@umontreal.ca.

ABSTRACT

Background: Plasma adiponectin is a significant correlate of the pro-inflammatory cardiometabolic risk profile associated with obesity and type 2 diabetes. Salivary pH is influenced by several cardiometabolic risk components such as inflammation, oxidation and numerous oral and systemic health modulators, including the menopausal status. This study aimed to assess the association between plasma adiponectin concentrations and salivary pH in women according to the menopausal status.

Method: Unstimulated saliva collection was performed in 151 Caucasian women of French-Canadian origin (53 premenopausal women (PMW) and 98 menopausal women (MW)). Student's t test, ANOVA and linear regression models were used to assess the association between plasma adiponectin concentrations and salivary pH.

Results: Plasma adiponectin levels increased as a function of salivary pH in the whole sample and among MW (r = 0.29 and r = 0.36, p < 0.001). The proportion of the variance of plasma adiponectin levels explained by the salivary pH (R2) was 10.8% (p < 0.001). Plasma adiponectin levels progressively increased across salivary pH quartiles (p = 0.005).

Conclusions: These results suggest that salivary pH is a significant correlate of plasma adiponectin levels in women. With the increasing prevalence of type 2 diabetes and obesity, new technologies should be developed to more easily monitor health status, disease onset and progression. Salivary pH, a simple, inexpensive and non-invasive measure, could be a very promising avenue.

No MeSH data available.


Related in: MedlinePlus

a) Association between plasma adiponectin levels and salivary pH in the whole sample, adjusting for age; b) Association between plasma adiponectin levels and salivary pH in premenopausal women and menopausal women, adjusting for age.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3306272&req=5

Figure 1: a) Association between plasma adiponectin levels and salivary pH in the whole sample, adjusting for age; b) Association between plasma adiponectin levels and salivary pH in premenopausal women and menopausal women, adjusting for age.

Mentions: As shown in Figure 1, plasma adiponectin levels increased as a function of salivary pH in the whole sample and among MW (r = 0.29 and r = 0.36, p < 0.001). Although the correlation did not reach significance level in PMW, the same trend was observed (r = 0.24; p = 0.086). Plasma adiponectin levels progressively increased across salivary pH quartiles (p < 0.005) in the whole sample (Figure 2).


Salivary pH as a marker of plasma adiponectin concentrations in Women.

Tremblay M, Loucif Y, Methot J, Brisson D, Gaudet D - Diabetol Metab Syndr (2012)

a) Association between plasma adiponectin levels and salivary pH in the whole sample, adjusting for age; b) Association between plasma adiponectin levels and salivary pH in premenopausal women and menopausal women, adjusting for age.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3306272&req=5

Figure 1: a) Association between plasma adiponectin levels and salivary pH in the whole sample, adjusting for age; b) Association between plasma adiponectin levels and salivary pH in premenopausal women and menopausal women, adjusting for age.
Mentions: As shown in Figure 1, plasma adiponectin levels increased as a function of salivary pH in the whole sample and among MW (r = 0.29 and r = 0.36, p < 0.001). Although the correlation did not reach significance level in PMW, the same trend was observed (r = 0.24; p = 0.086). Plasma adiponectin levels progressively increased across salivary pH quartiles (p < 0.005) in the whole sample (Figure 2).

Bottom Line: Plasma adiponectin levels progressively increased across salivary pH quartiles (p = 0.005).These results suggest that salivary pH is a significant correlate of plasma adiponectin levels in women.Salivary pH, a simple, inexpensive and non-invasive measure, could be a very promising avenue.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Medicine, Université de Montréal, ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, QC, Canada. daniel.gaudet@umontreal.ca.

ABSTRACT

Background: Plasma adiponectin is a significant correlate of the pro-inflammatory cardiometabolic risk profile associated with obesity and type 2 diabetes. Salivary pH is influenced by several cardiometabolic risk components such as inflammation, oxidation and numerous oral and systemic health modulators, including the menopausal status. This study aimed to assess the association between plasma adiponectin concentrations and salivary pH in women according to the menopausal status.

Method: Unstimulated saliva collection was performed in 151 Caucasian women of French-Canadian origin (53 premenopausal women (PMW) and 98 menopausal women (MW)). Student's t test, ANOVA and linear regression models were used to assess the association between plasma adiponectin concentrations and salivary pH.

Results: Plasma adiponectin levels increased as a function of salivary pH in the whole sample and among MW (r = 0.29 and r = 0.36, p < 0.001). The proportion of the variance of plasma adiponectin levels explained by the salivary pH (R2) was 10.8% (p < 0.001). Plasma adiponectin levels progressively increased across salivary pH quartiles (p = 0.005).

Conclusions: These results suggest that salivary pH is a significant correlate of plasma adiponectin levels in women. With the increasing prevalence of type 2 diabetes and obesity, new technologies should be developed to more easily monitor health status, disease onset and progression. Salivary pH, a simple, inexpensive and non-invasive measure, could be a very promising avenue.

No MeSH data available.


Related in: MedlinePlus