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Support of the laboratory in the diagnosis of fungal ocular infections.

Vanzzini Zago V, Alcantara Castro M, Naranjo Tackman R - Int J Inflam (2012)

Bottom Line: We describe the microbiological diagnosis in palpebral mycose; in keratitis caused by Fusarium, Aspergillus, Candida, and melanized fungi; endophthalmitis; one Histoplasma scleritis and one mucormycosis.Correct diagnosis is important because an early medical treatment gives a better prognosis for visual acuity.In some cases, fungal infections are misdiagnosed and the antifungal treatment is delayed.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Microbiology, Asociación para Evitar la Ceguera en México Hospital "Dr. Luis Sánchez-Bulnes", Vicente Garcia Torres No. 46, 04030 Coyoacán, DF, Mexico.

ABSTRACT
This is a retrospective, and descriptive study about the support that the laboratory of microbiology aids can provide in the diagnosis of ocular infections in patients whom were attended a tertiary-care hospital in México City in a 10-year-time period. We describe the microbiological diagnosis in palpebral mycose; in keratitis caused by Fusarium, Aspergillus, Candida, and melanized fungi; endophthalmitis; one Histoplasma scleritis and one mucormycosis. Nowadays, ocular fungal infections are more often diagnosed, because there is more clinical suspicion and there are easy laboratory confirmations. Correct diagnosis is important because an early medical treatment gives a better prognosis for visual acuity. In some cases, fungal infections are misdiagnosed and the antifungal treatment is delayed.

No MeSH data available.


Related in: MedlinePlus

Microscopic view of fungal cells in a corneal sample smear with calcofluor and epifluorescent light ×400.
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fig7: Microscopic view of fungal cells in a corneal sample smear with calcofluor and epifluorescent light ×400.

Mentions: In the corneal sample smears, the hyphae showed septate cells and, in calcofluor stain technique, were indistinguishable to other moulds (Figure 7). In cultures, Aspergillus showed cottony white-green, or green-grey or brown-black color upon the specie colonies, with its characteristics conidiophores monoseriate or biseriate for its identification, and round to oval conidia. In our patient serial study, Aspergillus was isolated in 26% of keratitis cases. Aspergillus fumigatus, A. nidulans, A. flavus, A. niger, and A. glaucus were the most identified species.


Support of the laboratory in the diagnosis of fungal ocular infections.

Vanzzini Zago V, Alcantara Castro M, Naranjo Tackman R - Int J Inflam (2012)

Microscopic view of fungal cells in a corneal sample smear with calcofluor and epifluorescent light ×400.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3303867&req=5

fig7: Microscopic view of fungal cells in a corneal sample smear with calcofluor and epifluorescent light ×400.
Mentions: In the corneal sample smears, the hyphae showed septate cells and, in calcofluor stain technique, were indistinguishable to other moulds (Figure 7). In cultures, Aspergillus showed cottony white-green, or green-grey or brown-black color upon the specie colonies, with its characteristics conidiophores monoseriate or biseriate for its identification, and round to oval conidia. In our patient serial study, Aspergillus was isolated in 26% of keratitis cases. Aspergillus fumigatus, A. nidulans, A. flavus, A. niger, and A. glaucus were the most identified species.

Bottom Line: We describe the microbiological diagnosis in palpebral mycose; in keratitis caused by Fusarium, Aspergillus, Candida, and melanized fungi; endophthalmitis; one Histoplasma scleritis and one mucormycosis.Correct diagnosis is important because an early medical treatment gives a better prognosis for visual acuity.In some cases, fungal infections are misdiagnosed and the antifungal treatment is delayed.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Microbiology, Asociación para Evitar la Ceguera en México Hospital "Dr. Luis Sánchez-Bulnes", Vicente Garcia Torres No. 46, 04030 Coyoacán, DF, Mexico.

ABSTRACT
This is a retrospective, and descriptive study about the support that the laboratory of microbiology aids can provide in the diagnosis of ocular infections in patients whom were attended a tertiary-care hospital in México City in a 10-year-time period. We describe the microbiological diagnosis in palpebral mycose; in keratitis caused by Fusarium, Aspergillus, Candida, and melanized fungi; endophthalmitis; one Histoplasma scleritis and one mucormycosis. Nowadays, ocular fungal infections are more often diagnosed, because there is more clinical suspicion and there are easy laboratory confirmations. Correct diagnosis is important because an early medical treatment gives a better prognosis for visual acuity. In some cases, fungal infections are misdiagnosed and the antifungal treatment is delayed.

No MeSH data available.


Related in: MedlinePlus