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Clear cell variant of intraosseous mucoepidermoid carcinoma: Report of a rare entity.

Varma S, Shameena P, Sudha S, Nair RG, Varghese IV - J Oral Maxillofac Pathol (2012)

Bottom Line: Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion.It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region.Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology and Microbiology, Government Dental College, Medical College PO, Calicut, India.

ABSTRACT
Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion. Abundance of clear cells in an intraosseous mucoepidermoid carcinoma may complicate its histopathologic diagnosis. It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region. Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

No MeSH data available.


Related in: MedlinePlus

Cyst like areas, epidermoid, and clear cells – H and E, ×100
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Figure 4: Cyst like areas, epidermoid, and clear cells – H and E, ×100

Mentions: H and E stained sections of the biopsy specimen showed cystic spaces filled with eosinophilic material, surrounded by epidermoid cells and sheets of large polygonal cells with centrally placed nuclei, clear cytoplasm, and sharply defined cytoplasmic borders [Figure 4]. The intervening connective tissue stroma was scanty. The sections were stained with mucicarmine and Periodic acid Schiff's reagent (PAS) to assess the nature of clear cells. The eosinophilic material in cyst like spaces was PAS and mucicarmine positive. Mucus-secreting cells were visualized through mucicarmine staining [Figure 5]. The clear cells retained PAS positivity after diastase digestion [Figure 6] with a focal positivity for mucicarmine [Figure 7]. Diagnosis of clear cell variant of intraosseous MEC was confirmed on this basis.


Clear cell variant of intraosseous mucoepidermoid carcinoma: Report of a rare entity.

Varma S, Shameena P, Sudha S, Nair RG, Varghese IV - J Oral Maxillofac Pathol (2012)

Cyst like areas, epidermoid, and clear cells – H and E, ×100
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3303511&req=5

Figure 4: Cyst like areas, epidermoid, and clear cells – H and E, ×100
Mentions: H and E stained sections of the biopsy specimen showed cystic spaces filled with eosinophilic material, surrounded by epidermoid cells and sheets of large polygonal cells with centrally placed nuclei, clear cytoplasm, and sharply defined cytoplasmic borders [Figure 4]. The intervening connective tissue stroma was scanty. The sections were stained with mucicarmine and Periodic acid Schiff's reagent (PAS) to assess the nature of clear cells. The eosinophilic material in cyst like spaces was PAS and mucicarmine positive. Mucus-secreting cells were visualized through mucicarmine staining [Figure 5]. The clear cells retained PAS positivity after diastase digestion [Figure 6] with a focal positivity for mucicarmine [Figure 7]. Diagnosis of clear cell variant of intraosseous MEC was confirmed on this basis.

Bottom Line: Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion.It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region.Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology and Microbiology, Government Dental College, Medical College PO, Calicut, India.

ABSTRACT
Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion. Abundance of clear cells in an intraosseous mucoepidermoid carcinoma may complicate its histopathologic diagnosis. It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region. Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

No MeSH data available.


Related in: MedlinePlus