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High-grade mucoepidermoid carcinoma of maxillary sinus.

Daryani D, Gopakumar R, Nagaraja A - J Oral Maxillofac Pathol (2012)

Bottom Line: Nonsquamous cancers of the maxillary sinus are even rarer as is evident from the limited data available on the clinical characteristics and outcomes.Mucoepidermoid carcinoma accounts for 13% of all malignancies occurring in maxillary sinus.We report a rare case of high-grade mucoepidermoid carcinoma of maxillary sinus in a 45-year-old female along with review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Syamala Reddy Dental College and Research Centre, Bangalore, India.

ABSTRACT
Malignant tumors of the paranasal sinus are uncommon, constituting less than 1% of all malignancies and 3% of all head and neck cancers. Nonsquamous cancers of the maxillary sinus are even rarer as is evident from the limited data available on the clinical characteristics and outcomes. Mucoepidermoid carcinoma accounts for 13% of all malignancies occurring in maxillary sinus. We report a rare case of high-grade mucoepidermoid carcinoma of maxillary sinus in a 45-year-old female along with review of the literature.

No MeSH data available.


Related in: MedlinePlus

Demonstrating extensive degree of cellular atypia (H and E staining, ×40 view)
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Figure 6: Demonstrating extensive degree of cellular atypia (H and E staining, ×40 view)

Mentions: The routine H and E stained sections revealed highly cellular stroma arranged haphazardly, in sheets and nests at areas. Tumor cells were seen containing eosinophilic cytoplasm and round to oval hyperchromatic pleomorphic nuclei with plenty of mitotic figures. Upon examination in higher magnification, a mixture of morphologically altered epidermoid cells, intermediate basaloid-like cells and mucous cells are observed of which epidermoid component is predominant [Figure 5]. The proliferation of epidermoid and intermediate components is in the form of sheets with some areas resembling squamous cell carcinoma. The lesional tissue show great variability in the composition of cells and many of them demonstrate extensive degree of cellular atypia. Production of mucin, formation of cyst-like areas is barely minimal. Areas that demonstrate clear appearing cells (vacuolated cytoplasm) and a minimal inflammatory infiltrate also characterize the lesional tissue. Adjacent skeletal muscle and tiny bony spicule was infiltrated by tumor cells [Figure 6]. The microscopic picture was suggestive of a high-grade mucoepidermoid carcinoma.


High-grade mucoepidermoid carcinoma of maxillary sinus.

Daryani D, Gopakumar R, Nagaraja A - J Oral Maxillofac Pathol (2012)

Demonstrating extensive degree of cellular atypia (H and E staining, ×40 view)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3303510&req=5

Figure 6: Demonstrating extensive degree of cellular atypia (H and E staining, ×40 view)
Mentions: The routine H and E stained sections revealed highly cellular stroma arranged haphazardly, in sheets and nests at areas. Tumor cells were seen containing eosinophilic cytoplasm and round to oval hyperchromatic pleomorphic nuclei with plenty of mitotic figures. Upon examination in higher magnification, a mixture of morphologically altered epidermoid cells, intermediate basaloid-like cells and mucous cells are observed of which epidermoid component is predominant [Figure 5]. The proliferation of epidermoid and intermediate components is in the form of sheets with some areas resembling squamous cell carcinoma. The lesional tissue show great variability in the composition of cells and many of them demonstrate extensive degree of cellular atypia. Production of mucin, formation of cyst-like areas is barely minimal. Areas that demonstrate clear appearing cells (vacuolated cytoplasm) and a minimal inflammatory infiltrate also characterize the lesional tissue. Adjacent skeletal muscle and tiny bony spicule was infiltrated by tumor cells [Figure 6]. The microscopic picture was suggestive of a high-grade mucoepidermoid carcinoma.

Bottom Line: Nonsquamous cancers of the maxillary sinus are even rarer as is evident from the limited data available on the clinical characteristics and outcomes.Mucoepidermoid carcinoma accounts for 13% of all malignancies occurring in maxillary sinus.We report a rare case of high-grade mucoepidermoid carcinoma of maxillary sinus in a 45-year-old female along with review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Syamala Reddy Dental College and Research Centre, Bangalore, India.

ABSTRACT
Malignant tumors of the paranasal sinus are uncommon, constituting less than 1% of all malignancies and 3% of all head and neck cancers. Nonsquamous cancers of the maxillary sinus are even rarer as is evident from the limited data available on the clinical characteristics and outcomes. Mucoepidermoid carcinoma accounts for 13% of all malignancies occurring in maxillary sinus. We report a rare case of high-grade mucoepidermoid carcinoma of maxillary sinus in a 45-year-old female along with review of the literature.

No MeSH data available.


Related in: MedlinePlus