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Metastasizing granular cell ameloblastoma.

Bansal A, Bhatnagar A, Saxena S - J Oral Maxillofac Pathol (2012)

Bottom Line: It accounts for 1% of all tumors and cysts arising in maxilla and mandible.Although it is locally invasive and has a marked tendency to recur, metastasis is rare.We report a case of granular cell ameloblastoma with metastasis to the cervical lymph node presenting in a 40-year-old Indian female.

View Article: PubMed Central - PubMed

Affiliation: National Institute of Pathology (Indian Council of Medical Research), Safdarjung Hospital Campus, New Delhi, India.

ABSTRACT
Ameloblastoma is a slow growing odontogenic epithelial tumor of jaw. It accounts for 1% of all tumors and cysts arising in maxilla and mandible. Although it is locally invasive and has a marked tendency to recur, metastasis is rare. Of the various histological patterns of ameloblastoma, the granular cell type is extremely rare accounting for 4% of ameloblastomas. We report a case of granular cell ameloblastoma with metastasis to the cervical lymph node presenting in a 40-year-old Indian female.

No MeSH data available.


Related in: MedlinePlus

Cells displaying cytoplasmic granularity with pyknotic nuclei, some of which are eccentric. (H and E, ×400)
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Figure 4: Cells displaying cytoplasmic granularity with pyknotic nuclei, some of which are eccentric. (H and E, ×400)

Mentions: Microscopic examination of the sections showed an encapsulated tumor of odontogenic origin. Tumor cells formed nests supported by fibrous connective tissue stroma [Figure 2]. At the periphery of the nests, there were columnar cells organized in a pallisaded fashion [Figure 3]. The inner cell mass showed round to polygonal cells with abundant granular cytoplasm and small pyknotic nuclei [Figure 4]. Parotid gland and muscle fibers were free from tumor cell infiltration. One lymph node showed tumor metastasis characterized by the presence of granular cells [Figure 5].


Metastasizing granular cell ameloblastoma.

Bansal A, Bhatnagar A, Saxena S - J Oral Maxillofac Pathol (2012)

Cells displaying cytoplasmic granularity with pyknotic nuclei, some of which are eccentric. (H and E, ×400)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3303505&req=5

Figure 4: Cells displaying cytoplasmic granularity with pyknotic nuclei, some of which are eccentric. (H and E, ×400)
Mentions: Microscopic examination of the sections showed an encapsulated tumor of odontogenic origin. Tumor cells formed nests supported by fibrous connective tissue stroma [Figure 2]. At the periphery of the nests, there were columnar cells organized in a pallisaded fashion [Figure 3]. The inner cell mass showed round to polygonal cells with abundant granular cytoplasm and small pyknotic nuclei [Figure 4]. Parotid gland and muscle fibers were free from tumor cell infiltration. One lymph node showed tumor metastasis characterized by the presence of granular cells [Figure 5].

Bottom Line: It accounts for 1% of all tumors and cysts arising in maxilla and mandible.Although it is locally invasive and has a marked tendency to recur, metastasis is rare.We report a case of granular cell ameloblastoma with metastasis to the cervical lymph node presenting in a 40-year-old Indian female.

View Article: PubMed Central - PubMed

Affiliation: National Institute of Pathology (Indian Council of Medical Research), Safdarjung Hospital Campus, New Delhi, India.

ABSTRACT
Ameloblastoma is a slow growing odontogenic epithelial tumor of jaw. It accounts for 1% of all tumors and cysts arising in maxilla and mandible. Although it is locally invasive and has a marked tendency to recur, metastasis is rare. Of the various histological patterns of ameloblastoma, the granular cell type is extremely rare accounting for 4% of ameloblastomas. We report a case of granular cell ameloblastoma with metastasis to the cervical lymph node presenting in a 40-year-old Indian female.

No MeSH data available.


Related in: MedlinePlus