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Paget's disease of the mandible.

Karunakaran K, Murugesan P, Rajeshwar G, Babu S - J Oral Maxillofac Pathol (2012)

Bottom Line: Paget's disease (PD) is a chronic progressive disease of the bone characterized by abnormal bone resorption and deposition affecting either single bone (monostotic) or many bones (polyostotic) with uncertain etiology.We report a case of isolated mandibular involvement in a 65-year-old female patient, clinically asymptomatic with abnormally increased alkaline phosphatase level (1 368.1 U/l).Although prevalence of PD is common in western countries, but rare in Asian chapter, that too isolated mandibular involvement, considering this fact, we report this case of PD for documentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology, J. K. K. Nataraja Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.

ABSTRACT
Paget's disease (PD) is a chronic progressive disease of the bone characterized by abnormal bone resorption and deposition affecting either single bone (monostotic) or many bones (polyostotic) with uncertain etiology. We report a case of isolated mandibular involvement in a 65-year-old female patient, clinically asymptomatic with abnormally increased alkaline phosphatase level (1 368.1 U/l). Although prevalence of PD is common in western countries, but rare in Asian chapter, that too isolated mandibular involvement, considering this fact, we report this case of PD for documentation.

No MeSH data available.


Related in: MedlinePlus

OPG shows hypercementosis of the teeth roots.
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Figure 3: OPG shows hypercementosis of the teeth roots.

Mentions: A 67-year-old female patient reported to a private dental clinic in Coimbatore, complaining of swelling in the lower jaw for past few years. History reveals a slow-progressive swelling with no other associated symptoms like pain, discharge, and non-responsive to any medication. Extra oral examination reveals broadening and widening of the lower facial view with thickened lower lip. Intra oral examination showed increased size and altered shape of the mandibular alveolar ridge, pseudo micrognathia of the maxillary arch [Figures 1 and 2], and partially edentulous, thickened cortical plate. Orthopantomograph shows hypercementosis with displacement of involved teeth, cortical thickening of the body of the mandible, and mixed radiolucent and radio opaque areas [Figure 3] on both sides of the mandible. Whole-body X-rays and scans were taken to ascertain the involvement of other bones [Figure 4], confirming that the lesion was restricted to mandible only.


Paget's disease of the mandible.

Karunakaran K, Murugesan P, Rajeshwar G, Babu S - J Oral Maxillofac Pathol (2012)

OPG shows hypercementosis of the teeth roots.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3303501&req=5

Figure 3: OPG shows hypercementosis of the teeth roots.
Mentions: A 67-year-old female patient reported to a private dental clinic in Coimbatore, complaining of swelling in the lower jaw for past few years. History reveals a slow-progressive swelling with no other associated symptoms like pain, discharge, and non-responsive to any medication. Extra oral examination reveals broadening and widening of the lower facial view with thickened lower lip. Intra oral examination showed increased size and altered shape of the mandibular alveolar ridge, pseudo micrognathia of the maxillary arch [Figures 1 and 2], and partially edentulous, thickened cortical plate. Orthopantomograph shows hypercementosis with displacement of involved teeth, cortical thickening of the body of the mandible, and mixed radiolucent and radio opaque areas [Figure 3] on both sides of the mandible. Whole-body X-rays and scans were taken to ascertain the involvement of other bones [Figure 4], confirming that the lesion was restricted to mandible only.

Bottom Line: Paget's disease (PD) is a chronic progressive disease of the bone characterized by abnormal bone resorption and deposition affecting either single bone (monostotic) or many bones (polyostotic) with uncertain etiology.We report a case of isolated mandibular involvement in a 65-year-old female patient, clinically asymptomatic with abnormally increased alkaline phosphatase level (1 368.1 U/l).Although prevalence of PD is common in western countries, but rare in Asian chapter, that too isolated mandibular involvement, considering this fact, we report this case of PD for documentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology, J. K. K. Nataraja Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.

ABSTRACT
Paget's disease (PD) is a chronic progressive disease of the bone characterized by abnormal bone resorption and deposition affecting either single bone (monostotic) or many bones (polyostotic) with uncertain etiology. We report a case of isolated mandibular involvement in a 65-year-old female patient, clinically asymptomatic with abnormally increased alkaline phosphatase level (1 368.1 U/l). Although prevalence of PD is common in western countries, but rare in Asian chapter, that too isolated mandibular involvement, considering this fact, we report this case of PD for documentation.

No MeSH data available.


Related in: MedlinePlus