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Posterior subhyaloid precipitates in cytomegalovirus retinitis.

Goldhardt R, Gregori NZ, Albini T, Yalamanchi S, Emanuelli A - J Ophthalmic Inflamm Infect (2011)

Bottom Line: This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis.A small case series was conducted.Inflammatory precipitates may collect in the posterior subhyaloid space in acute CMV retinitis and resolve with treatment.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Section, Miami Veterans Affairs Medical Center, 1201 NW 16th Ave, Miami, FL, 33125, USA, rgoldhardt@yahoo.com.br.

ABSTRACT

Purpose: This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis.

Methods: A small case series was conducted.

Results: Clinical findings, treatment, and follow-up of two patients with CMV and PSPs are presented.

Conclusions: Inflammatory precipitates may collect in the posterior subhyaloid space in acute CMV retinitis and resolve with treatment.

No MeSH data available.


Related in: MedlinePlus

a Fundus photos 2 months after PPV with silicone oil and ganciclovir implant. b OCT showing attached macula
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Fig4: a Fundus photos 2 months after PPV with silicone oil and ganciclovir implant. b OCT showing attached macula

Mentions: Four months after the diagnosis, while still on oral valganciclovir maintenance dose, the localized RD remained stable with attached posterior hyaloid (Fig. 3a, b). The PSPs resolved, but a new small necrotic lesion appeared superior to the optic nerve. A week later, another satellite lesion developed, and the patient’s oral valganciclovir dose was increased from 900 mg daily to 900 mg twice daily. In addition, an intravitreal ganciclovir injection (2 mg/0.05 ml) was administered (Fig. 3c). CD4 was 57/mm3. The vision in the left eye was stable at 20/25. One week after intravitreal injection of ganciclovir, the RD progressed threatening the macula and lens-sparing pars plana vitrectomy (PPV) with silicone oil and ganciclovir implant (Vitrasert) was performed. Four months after the surgery, vision was 20/25 and retina was attached under silicone oil (Fig. 4a, b). CD4 increased to 125/mm3.Fig. 3


Posterior subhyaloid precipitates in cytomegalovirus retinitis.

Goldhardt R, Gregori NZ, Albini T, Yalamanchi S, Emanuelli A - J Ophthalmic Inflamm Infect (2011)

a Fundus photos 2 months after PPV with silicone oil and ganciclovir implant. b OCT showing attached macula
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3302996&req=5

Fig4: a Fundus photos 2 months after PPV with silicone oil and ganciclovir implant. b OCT showing attached macula
Mentions: Four months after the diagnosis, while still on oral valganciclovir maintenance dose, the localized RD remained stable with attached posterior hyaloid (Fig. 3a, b). The PSPs resolved, but a new small necrotic lesion appeared superior to the optic nerve. A week later, another satellite lesion developed, and the patient’s oral valganciclovir dose was increased from 900 mg daily to 900 mg twice daily. In addition, an intravitreal ganciclovir injection (2 mg/0.05 ml) was administered (Fig. 3c). CD4 was 57/mm3. The vision in the left eye was stable at 20/25. One week after intravitreal injection of ganciclovir, the RD progressed threatening the macula and lens-sparing pars plana vitrectomy (PPV) with silicone oil and ganciclovir implant (Vitrasert) was performed. Four months after the surgery, vision was 20/25 and retina was attached under silicone oil (Fig. 4a, b). CD4 increased to 125/mm3.Fig. 3

Bottom Line: This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis.A small case series was conducted.Inflammatory precipitates may collect in the posterior subhyaloid space in acute CMV retinitis and resolve with treatment.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Section, Miami Veterans Affairs Medical Center, 1201 NW 16th Ave, Miami, FL, 33125, USA, rgoldhardt@yahoo.com.br.

ABSTRACT

Purpose: This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis.

Methods: A small case series was conducted.

Results: Clinical findings, treatment, and follow-up of two patients with CMV and PSPs are presented.

Conclusions: Inflammatory precipitates may collect in the posterior subhyaloid space in acute CMV retinitis and resolve with treatment.

No MeSH data available.


Related in: MedlinePlus