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The use of lithium dilution for measuring cardiac output and shunt fraction in patients during venovenous extracorporeal membrane oxygenation: a feasibility study in a flow model

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Diagram of the flow model. Pump C representing the cardiac output was set up to draw 3 l/min from the 50 l bucket of saline. Some of this flow passed via the ECMO pump (E) through the membrane oxygenator (M) and then either recirculated through the ECMO circuit via the shunt pump (S) or returned to the bucket. LiCI injections were made just downstream of the oxygenator and dilution curves were recorded simultaneously by the sensors A and B.
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Figure 1: Diagram of the flow model. Pump C representing the cardiac output was set up to draw 3 l/min from the 50 l bucket of saline. Some of this flow passed via the ECMO pump (E) through the membrane oxygenator (M) and then either recirculated through the ECMO circuit via the shunt pump (S) or returned to the bucket. LiCI injections were made just downstream of the oxygenator and dilution curves were recorded simultaneously by the sensors A and B.

Mentions: The patient circulation and ECMO circuit were represented by a flow model (Fig. 1). Pump C was set at 3 1/min throughout. Pump E (ECMO) and S (shunt) were varied to provide 3 shunt fractions, (approximately 12, 25, 50%) at each of 3 ECMO flow rates (approximately 0.5, 1.0 and 2.0 l/min). Following a bolus injection of lithium chloride (0.15 mmol), its dilution curves were recorded simultaneously by sensors A and B (see Fig. 1). The flows through pump S and pump C were calculated from the 9 pairs of lithium dilution curves and compared to the actual flows delivered.


The use of lithium dilution for measuring cardiac output and shunt fraction in patients during venovenous extracorporeal membrane oxygenation: a feasibility study in a flow model
Diagram of the flow model. Pump C representing the cardiac output was set up to draw 3 l/min from the 50 l bucket of saline. Some of this flow passed via the ECMO pump (E) through the membrane oxygenator (M) and then either recirculated through the ECMO circuit via the shunt pump (S) or returned to the bucket. LiCI injections were made just downstream of the oxygenator and dilution curves were recorded simultaneously by the sensors A and B.
© Copyright Policy
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3301318&req=5

Figure 1: Diagram of the flow model. Pump C representing the cardiac output was set up to draw 3 l/min from the 50 l bucket of saline. Some of this flow passed via the ECMO pump (E) through the membrane oxygenator (M) and then either recirculated through the ECMO circuit via the shunt pump (S) or returned to the bucket. LiCI injections were made just downstream of the oxygenator and dilution curves were recorded simultaneously by the sensors A and B.
Mentions: The patient circulation and ECMO circuit were represented by a flow model (Fig. 1). Pump C was set at 3 1/min throughout. Pump E (ECMO) and S (shunt) were varied to provide 3 shunt fractions, (approximately 12, 25, 50%) at each of 3 ECMO flow rates (approximately 0.5, 1.0 and 2.0 l/min). Following a bolus injection of lithium chloride (0.15 mmol), its dilution curves were recorded simultaneously by sensors A and B (see Fig. 1). The flows through pump S and pump C were calculated from the 9 pairs of lithium dilution curves and compared to the actual flows delivered.

View Article: PubMed Central - HTML

No MeSH data available.


Related in: MedlinePlus