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High oxygen treatment during preparation of children for open-heart surgery leads to a decrease in total antioxidant capacity

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Average TEAC and triglyceride values in infants with VSD or TOF. Shown are changes in TEAC and triglyceride values before, during (grey area) and after CPB.
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Figure 1: Average TEAC and triglyceride values in infants with VSD or TOF. Shown are changes in TEAC and triglyceride values before, during (grey area) and after CPB.

Mentions: Total antioxidant capacity was decreased shortly after the onset of surgery in plasma of children (aged 8-14 months) treated for ventricular septal defect (VSD; n = 17) and tetralogy of Fallot (TOF; n = 15). Figure 1 shows a significant (Friedman test; P < 0.05) decrease in both VSD and TOF from time point 1.1 (induction of anaesthesia) to time point 2 (heparin administration before CPB). Decrease in TEAC values can therefore not be a result of haemodilution during CPB. This was confirmed by the fact that total plasma triglyceride values did not decrease between these time points. Shortly after CPB (time point 4) the TEAC values were already significantly (P < 0.05) higher than at time point 3 (10 min after the onset of CPB), and they returned to normal during the 4 h after the operation and remained normal thereafter.


High oxygen treatment during preparation of children for open-heart surgery leads to a decrease in total antioxidant capacity
Average TEAC and triglyceride values in infants with VSD or TOF. Shown are changes in TEAC and triglyceride values before, during (grey area) and after CPB.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3300093&req=5

Figure 1: Average TEAC and triglyceride values in infants with VSD or TOF. Shown are changes in TEAC and triglyceride values before, during (grey area) and after CPB.
Mentions: Total antioxidant capacity was decreased shortly after the onset of surgery in plasma of children (aged 8-14 months) treated for ventricular septal defect (VSD; n = 17) and tetralogy of Fallot (TOF; n = 15). Figure 1 shows a significant (Friedman test; P < 0.05) decrease in both VSD and TOF from time point 1.1 (induction of anaesthesia) to time point 2 (heparin administration before CPB). Decrease in TEAC values can therefore not be a result of haemodilution during CPB. This was confirmed by the fact that total plasma triglyceride values did not decrease between these time points. Shortly after CPB (time point 4) the TEAC values were already significantly (P < 0.05) higher than at time point 3 (10 min after the onset of CPB), and they returned to normal during the 4 h after the operation and remained normal thereafter.

View Article: PubMed Central - HTML

No MeSH data available.