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Analysis on descriptions of precautionary statements in package inserts of medicines.

Nabeta K, Kimura M, Ohkura M, Tsuchiya F - Drug Healthc Patient Saf (2012)

Bottom Line: WE FOUND THAT THERE ARE FOUR TYPES OF STATEMENTS: direct orders such as " " (use), causative orders such as " " (make someone use), direct interdictions such as " " (do not use), and causative interdictions such as " " (do not make user use).As for words representing timing, we extracted six groups: "at the time of delivery," "at the time of preparation," "in use," "after use," and "at the time of storage." From these results, we obtained points of consideration concerning the subjects of orders in the statements and timing of their execution.It should contain information such as the actions described in the statement, the flag to express an order or interdiction, the subject to be ordered, and the timing.

View Article: PubMed Central - PubMed

Affiliation: Graduate School of Engineering and Science, Shibaura Institute of Technology, Toyosu 3-7-5, Koto-ku, Tokyo, 135-8548 Japan.

ABSTRACT

Background: To prevent medical accidents, users must be informed of the cautions written in medical package inserts. To realize countermeasures by utilizing information systems, we must also implement a drug information database. However, this is not easy to develop, since the descriptions in package inserts are too complex and their information poorly structured. It is necessary to analyze package insert information and propose a data structure.

Methods: We analyzed the descriptions of 'precautions for application' in package inserts via text mining methods. In order to summarize statements, we applied dependency analysis to statements and visualized their relations between predicate words and other words. Furthermore, we extracted words representing timing to execute the order.

Results: WE FOUND THAT THERE ARE FOUR TYPES OF STATEMENTS: direct orders such as " " (use), causative orders such as " " (make someone use), direct interdictions such as " " (do not use), and causative interdictions such as " " (do not make user use). As for words representing timing, we extracted six groups: "at the time of delivery," "at the time of preparation," "in use," "after use," and "at the time of storage." From these results, we obtained points of consideration concerning the subjects of orders in the statements and timing of their execution.

Conclusion: From the obtained knowledge, we can define the information structure used to describe the precautionary statement. It should contain information such as the actions described in the statement, the flag to express an order or interdiction, the subject to be ordered, and the timing.

No MeSH data available.


Network of words related to direct orders (threshold: 90).
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f2-dhps-4-019: Network of words related to direct orders (threshold: 90).

Mentions: We aggregated ternaries, a verb, a case marker, and the verb modifier, which also appears in the segment containing the case marker. After aggregation, we visualized the ternaries as nodes of a network to find major information in the order statement concerning the four cases, which are direct order, interdiction, causative order, and causative interdiction. In the network, the nodes are collected verbs, case markers, and keywords, and the edges express the connections among them, while their frequencies are expressed as their width. The threshold of appearance frequencies in the data limits the nodes and edges in Figures 2–5.


Analysis on descriptions of precautionary statements in package inserts of medicines.

Nabeta K, Kimura M, Ohkura M, Tsuchiya F - Drug Healthc Patient Saf (2012)

Network of words related to direct orders (threshold: 90).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3295621&req=5

f2-dhps-4-019: Network of words related to direct orders (threshold: 90).
Mentions: We aggregated ternaries, a verb, a case marker, and the verb modifier, which also appears in the segment containing the case marker. After aggregation, we visualized the ternaries as nodes of a network to find major information in the order statement concerning the four cases, which are direct order, interdiction, causative order, and causative interdiction. In the network, the nodes are collected verbs, case markers, and keywords, and the edges express the connections among them, while their frequencies are expressed as their width. The threshold of appearance frequencies in the data limits the nodes and edges in Figures 2–5.

Bottom Line: WE FOUND THAT THERE ARE FOUR TYPES OF STATEMENTS: direct orders such as " " (use), causative orders such as " " (make someone use), direct interdictions such as " " (do not use), and causative interdictions such as " " (do not make user use).As for words representing timing, we extracted six groups: "at the time of delivery," "at the time of preparation," "in use," "after use," and "at the time of storage." From these results, we obtained points of consideration concerning the subjects of orders in the statements and timing of their execution.It should contain information such as the actions described in the statement, the flag to express an order or interdiction, the subject to be ordered, and the timing.

View Article: PubMed Central - PubMed

Affiliation: Graduate School of Engineering and Science, Shibaura Institute of Technology, Toyosu 3-7-5, Koto-ku, Tokyo, 135-8548 Japan.

ABSTRACT

Background: To prevent medical accidents, users must be informed of the cautions written in medical package inserts. To realize countermeasures by utilizing information systems, we must also implement a drug information database. However, this is not easy to develop, since the descriptions in package inserts are too complex and their information poorly structured. It is necessary to analyze package insert information and propose a data structure.

Methods: We analyzed the descriptions of 'precautions for application' in package inserts via text mining methods. In order to summarize statements, we applied dependency analysis to statements and visualized their relations between predicate words and other words. Furthermore, we extracted words representing timing to execute the order.

Results: WE FOUND THAT THERE ARE FOUR TYPES OF STATEMENTS: direct orders such as " " (use), causative orders such as " " (make someone use), direct interdictions such as " " (do not use), and causative interdictions such as " " (do not make user use). As for words representing timing, we extracted six groups: "at the time of delivery," "at the time of preparation," "in use," "after use," and "at the time of storage." From these results, we obtained points of consideration concerning the subjects of orders in the statements and timing of their execution.

Conclusion: From the obtained knowledge, we can define the information structure used to describe the precautionary statement. It should contain information such as the actions described in the statement, the flag to express an order or interdiction, the subject to be ordered, and the timing.

No MeSH data available.