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Brain metastasis of nasopharyngeal carcinoma: a case report and literature review.

Kaidar-Person O, Kuten J, Atrash F, Billan S, Kuten A - Case Rep Med (2012)

Bottom Line: Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon.The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis.References of the published papers were also reviewed.

View Article: PubMed Central - PubMed

Affiliation: Oncology Institute, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, Israel.

ABSTRACT
Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon. The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis. A PubMed database search was conducted to review the existing literature regarding brain metastases of NPC, using the search terms "nasopharyngeal neoplasia," "nasopharyngeal carcinoma," "nasopharynx," "radiotherapy," "central nervous system," and "brain" in section of "Title/Abstract." The articles were first evaluated by title and then by abstract, and thereafter appropriate manuscripts were evaluated by full text. References of the published papers were also reviewed.

No MeSH data available.


Related in: MedlinePlus

FDG-PET/CT scan performed three months after completion of chemoradiotherapy showed pathological uptakes in the left cervical lymph nodes.
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fig2: FDG-PET/CT scan performed three months after completion of chemoradiotherapy showed pathological uptakes in the left cervical lymph nodes.

Mentions: Functional imaging is still under investigation in NPC; however, some reports suggested that a high standardized uptake value (SUV) on FDG-PET/CT scans has a potential value as a prognostic indicator. High pretreatment SUV had a significantly lower 3-year disease-free survival than patients with lower FDG uptake [13]. The patient present in this case had evidence of advance disease in FDG-PET/CT and relatively high pretreatment SUV count. FDG-PET/CT scan performed three months after completion of chemo-radiotherapy showed pathological uptakes in the left cervical lymph nodes with an SUV of 5 (Figure 2); however, there is no concrete evidence in regard to the value of posttreatment SUV as an indicator for survival [5, 13].


Brain metastasis of nasopharyngeal carcinoma: a case report and literature review.

Kaidar-Person O, Kuten J, Atrash F, Billan S, Kuten A - Case Rep Med (2012)

FDG-PET/CT scan performed three months after completion of chemoradiotherapy showed pathological uptakes in the left cervical lymph nodes.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3295537&req=5

fig2: FDG-PET/CT scan performed three months after completion of chemoradiotherapy showed pathological uptakes in the left cervical lymph nodes.
Mentions: Functional imaging is still under investigation in NPC; however, some reports suggested that a high standardized uptake value (SUV) on FDG-PET/CT scans has a potential value as a prognostic indicator. High pretreatment SUV had a significantly lower 3-year disease-free survival than patients with lower FDG uptake [13]. The patient present in this case had evidence of advance disease in FDG-PET/CT and relatively high pretreatment SUV count. FDG-PET/CT scan performed three months after completion of chemo-radiotherapy showed pathological uptakes in the left cervical lymph nodes with an SUV of 5 (Figure 2); however, there is no concrete evidence in regard to the value of posttreatment SUV as an indicator for survival [5, 13].

Bottom Line: Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon.The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis.References of the published papers were also reviewed.

View Article: PubMed Central - PubMed

Affiliation: Oncology Institute, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, Israel.

ABSTRACT
Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon. The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis. A PubMed database search was conducted to review the existing literature regarding brain metastases of NPC, using the search terms "nasopharyngeal neoplasia," "nasopharyngeal carcinoma," "nasopharynx," "radiotherapy," "central nervous system," and "brain" in section of "Title/Abstract." The articles were first evaluated by title and then by abstract, and thereafter appropriate manuscripts were evaluated by full text. References of the published papers were also reviewed.

No MeSH data available.


Related in: MedlinePlus