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Assessing trends and predictors of tuberculosis in Taiwan.

Liao CM, Hsieh NH, Huang TL, Cheng YH, Lin YJ, Chio CP, Chen SC, Ling MP - BMC Public Health (2012)

Bottom Line: The generalized regression models were used to examine the potential predictors for the monthly TB incidence in regional and national scales.We found that (i) in Taiwan the average TB incidence was 68 per 100,000 population with mortality rate of 0.036 person-1 yr-1, (ii) the highest TB incidence rate was found in eastern Taiwan (116 per 100,000 population) with the largest proportion of TB relapse cases (8.17%), (iii) seasonality, aborigines, gender, and age had a consistent and dominant role in constructing TB incidence patterns in Taiwan, and (iv) gender, time trend, and 2-month lag maximum temperature showed strong association with TB trends in aboriginal subpopulations.The proposed Poisson regression model is capable of forecasting patterns of TB incidence at regional and national scales.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan 10617, Republic of China. cmliao@ntu.edu.tw

ABSTRACT

Background: Variety of environmental and individual factors can cause tuberculosis (TB) incidence change. The purpose of this study was to assess the characteristics of TB trends in the period 2004 - 2008 in Taiwan by month, year, gender, age, temperature, seasonality, and aborigines.

Methods: The generalized regression models were used to examine the potential predictors for the monthly TB incidence in regional and national scales.

Results: We found that (i) in Taiwan the average TB incidence was 68 per 100,000 population with mortality rate of 0.036 person-1 yr-1, (ii) the highest TB incidence rate was found in eastern Taiwan (116 per 100,000 population) with the largest proportion of TB relapse cases (8.17%), (iii) seasonality, aborigines, gender, and age had a consistent and dominant role in constructing TB incidence patterns in Taiwan, and (iv) gender, time trend, and 2-month lag maximum temperature showed strong association with TB trends in aboriginal subpopulations.

Conclusions: The proposed Poisson regression model is capable of forecasting patterns of TB incidence at regional and national scales. This study suggested that assessment of TB trends in eastern Taiwan presents an important opportunity for understanding the time-series dynamics and control of TB infections, given that this is the typical host demography in regions where these infections remain major public health problems.

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Time series of TB incidence rate with mean temperature in (a) northern, (b) central, (c) eastern Hwa-Tung, (d) southern, (e) southern Kao-Ping, and (f) island regions, respectively. (g) Region-specific contributions of TB incidence in Taiwan.
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Figure 2: Time series of TB incidence rate with mean temperature in (a) northern, (b) central, (c) eastern Hwa-Tung, (d) southern, (e) southern Kao-Ping, and (f) island regions, respectively. (g) Region-specific contributions of TB incidence in Taiwan.

Mentions: Figure 1 demonstrates the time-series dynamics of gender-, age group-, and subpopulation-specific monthly confirmed TB cases together with mean, maximum, and minimum temperatures in Taiwan region in the period 2004-2008. The time-series of TB incidence rate with mean temperature in northern, central, southern, southern Kao-Ping, eastern Hwa-Tung, and island regions were illustrated in Figure 2 Our result indicates that Hwa-Tung region contributed nearly 27% of TB incidence in Taiwan in the period 2004-2008 (Figure 2g). We thus chose Hwalien and Taitung Counties as our study areas compared to Taiwan.


Assessing trends and predictors of tuberculosis in Taiwan.

Liao CM, Hsieh NH, Huang TL, Cheng YH, Lin YJ, Chio CP, Chen SC, Ling MP - BMC Public Health (2012)

Time series of TB incidence rate with mean temperature in (a) northern, (b) central, (c) eastern Hwa-Tung, (d) southern, (e) southern Kao-Ping, and (f) island regions, respectively. (g) Region-specific contributions of TB incidence in Taiwan.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3285518&req=5

Figure 2: Time series of TB incidence rate with mean temperature in (a) northern, (b) central, (c) eastern Hwa-Tung, (d) southern, (e) southern Kao-Ping, and (f) island regions, respectively. (g) Region-specific contributions of TB incidence in Taiwan.
Mentions: Figure 1 demonstrates the time-series dynamics of gender-, age group-, and subpopulation-specific monthly confirmed TB cases together with mean, maximum, and minimum temperatures in Taiwan region in the period 2004-2008. The time-series of TB incidence rate with mean temperature in northern, central, southern, southern Kao-Ping, eastern Hwa-Tung, and island regions were illustrated in Figure 2 Our result indicates that Hwa-Tung region contributed nearly 27% of TB incidence in Taiwan in the period 2004-2008 (Figure 2g). We thus chose Hwalien and Taitung Counties as our study areas compared to Taiwan.

Bottom Line: The generalized regression models were used to examine the potential predictors for the monthly TB incidence in regional and national scales.We found that (i) in Taiwan the average TB incidence was 68 per 100,000 population with mortality rate of 0.036 person-1 yr-1, (ii) the highest TB incidence rate was found in eastern Taiwan (116 per 100,000 population) with the largest proportion of TB relapse cases (8.17%), (iii) seasonality, aborigines, gender, and age had a consistent and dominant role in constructing TB incidence patterns in Taiwan, and (iv) gender, time trend, and 2-month lag maximum temperature showed strong association with TB trends in aboriginal subpopulations.The proposed Poisson regression model is capable of forecasting patterns of TB incidence at regional and national scales.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan 10617, Republic of China. cmliao@ntu.edu.tw

ABSTRACT

Background: Variety of environmental and individual factors can cause tuberculosis (TB) incidence change. The purpose of this study was to assess the characteristics of TB trends in the period 2004 - 2008 in Taiwan by month, year, gender, age, temperature, seasonality, and aborigines.

Methods: The generalized regression models were used to examine the potential predictors for the monthly TB incidence in regional and national scales.

Results: We found that (i) in Taiwan the average TB incidence was 68 per 100,000 population with mortality rate of 0.036 person-1 yr-1, (ii) the highest TB incidence rate was found in eastern Taiwan (116 per 100,000 population) with the largest proportion of TB relapse cases (8.17%), (iii) seasonality, aborigines, gender, and age had a consistent and dominant role in constructing TB incidence patterns in Taiwan, and (iv) gender, time trend, and 2-month lag maximum temperature showed strong association with TB trends in aboriginal subpopulations.

Conclusions: The proposed Poisson regression model is capable of forecasting patterns of TB incidence at regional and national scales. This study suggested that assessment of TB trends in eastern Taiwan presents an important opportunity for understanding the time-series dynamics and control of TB infections, given that this is the typical host demography in regions where these infections remain major public health problems.

Show MeSH
Related in: MedlinePlus