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Pseudotumoral tracheobronchial amyloidosis mimicking asthma: a case report.

Serraj M, Kamaoui I, Znati K, Kouara S, Sahnoune F, Amara B, Biaze ME, Tizniti S, Amarti A, Benjelloun MC - J Med Case Rep (2012)

Bottom Line: Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma.She successfully received an endoscopic resection.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Lung Disease, Hassan II University Hospital of Fez, Fez, Morocco. moonserraj@yahoo.fr.

ABSTRACT

Introduction: Tracheobronchial amyloidosis is an uncommon localized form of amyloidosis that can simulate a tracheal tumor. Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.

Case presentation: We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma. A bronchoscopy revealed a tumor formation of her trachea; multiples biopsies were performed and a diagnosis made of amyloid light-chain amyloidosis. She successfully received an endoscopic resection.

Conclusion: This case highlights the importance of routinely carrying out an endoscopy in any patient complaining of atypical bronchial symptoms or with uncontrolled asthma. Tracheal amyloidosis is a rare disease, confirmed by histological examination of bronchial biopsies, and the treatment of choice is based on the bronchoscopic resection.

No MeSH data available.


Related in: MedlinePlus

Bronchoscopy findings. Circumferential and irregular tracheal tumor with a significant reduction of her tracheal caliber.
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Figure 2: Bronchoscopy findings. Circumferential and irregular tracheal tumor with a significant reduction of her tracheal caliber.

Mentions: Bronchoscopy was performed and showed a yellowish tumor formation just below her vocal cords, extending along the entire height of her trachea and reducing its diameter by more than 50%. This lesion was larger in the posterior wall and covered the side walls of her trachea. The carina was normal (Figure 2).


Pseudotumoral tracheobronchial amyloidosis mimicking asthma: a case report.

Serraj M, Kamaoui I, Znati K, Kouara S, Sahnoune F, Amara B, Biaze ME, Tizniti S, Amarti A, Benjelloun MC - J Med Case Rep (2012)

Bronchoscopy findings. Circumferential and irregular tracheal tumor with a significant reduction of her tracheal caliber.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3285053&req=5

Figure 2: Bronchoscopy findings. Circumferential and irregular tracheal tumor with a significant reduction of her tracheal caliber.
Mentions: Bronchoscopy was performed and showed a yellowish tumor formation just below her vocal cords, extending along the entire height of her trachea and reducing its diameter by more than 50%. This lesion was larger in the posterior wall and covered the side walls of her trachea. The carina was normal (Figure 2).

Bottom Line: Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma.She successfully received an endoscopic resection.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Lung Disease, Hassan II University Hospital of Fez, Fez, Morocco. moonserraj@yahoo.fr.

ABSTRACT

Introduction: Tracheobronchial amyloidosis is an uncommon localized form of amyloidosis that can simulate a tracheal tumor. Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.

Case presentation: We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma. A bronchoscopy revealed a tumor formation of her trachea; multiples biopsies were performed and a diagnosis made of amyloid light-chain amyloidosis. She successfully received an endoscopic resection.

Conclusion: This case highlights the importance of routinely carrying out an endoscopy in any patient complaining of atypical bronchial symptoms or with uncontrolled asthma. Tracheal amyloidosis is a rare disease, confirmed by histological examination of bronchial biopsies, and the treatment of choice is based on the bronchoscopic resection.

No MeSH data available.


Related in: MedlinePlus