Limits...
Trapping Iron Oxide into Hollow Gold Nanoparticles

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Synthesis of the core/shell-structured Fe3O4/Au nanoparticles by trapping Fe3O4 inside hollow Au nanoparticles is described. The produced composite nanoparticles are strongly magnetic with their surface plasmon resonance peaks in the near infrared region (wavelength from 700 to 800 nm), combining desirable magnetic and plasmonic properties into one nanoparticle. They are particularly suitable for in vivo diagnostic and therapeutic applications. The intact Au surface provides convenient anchorage sites for attachment of targeting molecules, and the particles can be activated by both near infrared lights and magnetic fields. As more and more hollow nanoparticles become available, this synthetic method would find general applications in the fabrication of core–shell multifunctional nanostructures.

No MeSH data available.


a and b HRTEM micrographs of PHAuNPs, showing the hollow core and the porous shell with pore size about 2–3 nm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3211847&req=5

Figure 1: a and b HRTEM micrographs of PHAuNPs, showing the hollow core and the porous shell with pore size about 2–3 nm.

Mentions: Synthesized PHAuNPs feature a sub-25-nm shell with a 50-nm hollow core. The shell is of porous nature with the pore size about 2–3 nm, as measured in the high-resolution transmission electron microscopy (HRTEM) image shown in Figure 1a. These nanoscale pores in the shell allow ions (Fe2+ and Fe3+) to diffuse into the hollow space in the core, where precipitation of Fe3O4 takes place upon the addition of OH-. The sizes of precipitated Fe3O4 nanoparticles (5–20 nm) are larger than the pore size, resulting in the trapping of the iron oxide nanoparticles inside the PHAuNPs (Figure 1b).


Trapping Iron Oxide into Hollow Gold Nanoparticles
a and b HRTEM micrographs of PHAuNPs, showing the hollow core and the porous shell with pore size about 2–3 nm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3211847&req=5

Figure 1: a and b HRTEM micrographs of PHAuNPs, showing the hollow core and the porous shell with pore size about 2–3 nm.
Mentions: Synthesized PHAuNPs feature a sub-25-nm shell with a 50-nm hollow core. The shell is of porous nature with the pore size about 2–3 nm, as measured in the high-resolution transmission electron microscopy (HRTEM) image shown in Figure 1a. These nanoscale pores in the shell allow ions (Fe2+ and Fe3+) to diffuse into the hollow space in the core, where precipitation of Fe3O4 takes place upon the addition of OH-. The sizes of precipitated Fe3O4 nanoparticles (5–20 nm) are larger than the pore size, resulting in the trapping of the iron oxide nanoparticles inside the PHAuNPs (Figure 1b).

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Synthesis of the core/shell-structured Fe3O4/Au nanoparticles by trapping Fe3O4 inside hollow Au nanoparticles is described. The produced composite nanoparticles are strongly magnetic with their surface plasmon resonance peaks in the near infrared region (wavelength from 700 to 800 nm), combining desirable magnetic and plasmonic properties into one nanoparticle. They are particularly suitable for in vivo diagnostic and therapeutic applications. The intact Au surface provides convenient anchorage sites for attachment of targeting molecules, and the particles can be activated by both near infrared lights and magnetic fields. As more and more hollow nanoparticles become available, this synthetic method would find general applications in the fabrication of core–shell multifunctional nanostructures.

No MeSH data available.