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A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles.

Auger A, Samuel J, Poncelet O, Raccurt O - Nanoscale Res Lett (2011)

Bottom Line: Nevertheless, the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent the encapsulation process from occurring.Mainly, the photophysical characteristics of the dyes are retained upon their encapsulation into the silica matrix, leading to fluorescent silica nanoparticles.This feature article surveys recent research progress on the fabrication strategies of these dye-doped silica nanoparticles.

View Article: PubMed Central - HTML - PubMed

Affiliation: CEA Grenoble, Department of Nano Materials, NanoChemistry and NanoSafety Laboratory (DRT/LITEN/DTNM/LCSN), 17 rue des Martyrs, 38054 Grenoble Cedex 9, France. aurelien.auger@cea.fr.

ABSTRACT
Numerous luminophores may be encapsulated into silica nanoparticles (< 100 nm) using the reverse microemulsion process. Nevertheless, the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent the encapsulation process from occurring. Such nanospheres represent attractive nanoplatforms for the development of biotargeted biocompatible luminescent tracers. Physical and chemical properties of the encapsulated molecules may be affected by the nanomatrix. This study examines the synthesis of different types of dispersed silica nanoparticles, the ability of the selected luminophores towards incorporation into the silica matrix of those nanoobjects as well as the photophysical properties of the produced dye-doped silica nanoparticles. The nanoparticles present mean diameters between 40 and 60 nm as shown by TEM analysis. Mainly, the photophysical characteristics of the dyes are retained upon their encapsulation into the silica matrix, leading to fluorescent silica nanoparticles. This feature article surveys recent research progress on the fabrication strategies of these dye-doped silica nanoparticles.

No MeSH data available.


Excitation and emission spectra of aqueous solutions of PPC and silica nanoparticles doped with PPC (1b, 2b, 3b and 4b).
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Figure 6: Excitation and emission spectra of aqueous solutions of PPC and silica nanoparticles doped with PPC (1b, 2b, 3b and 4b).

Mentions: Further incorporation of flat and rigid aromatic core organic dye has been investigated. The PPC porphyrin was chosen due to the structural similarity to the planar PABI molecule. But, exhibiting fluorescence, the PPC porphyrin was chosen to study the impact of encapsulation towards the fluorescent properties of this family of compounds. Indeed the PABI and the PPC molecules possess an aromatic core consisting of 18-π electrons, which emphasise the stability and the electrochromic properties of this family of intensely coloured dyes. The PPC dye exhibits fluorescence whereas the PABI detection was limited to absorption measurements. Excitation and emission spectra of a pure aqueous solution of PPC are illustrated in Figure 6.


A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles.

Auger A, Samuel J, Poncelet O, Raccurt O - Nanoscale Res Lett (2011)

Excitation and emission spectra of aqueous solutions of PPC and silica nanoparticles doped with PPC (1b, 2b, 3b and 4b).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3211415&req=5

Figure 6: Excitation and emission spectra of aqueous solutions of PPC and silica nanoparticles doped with PPC (1b, 2b, 3b and 4b).
Mentions: Further incorporation of flat and rigid aromatic core organic dye has been investigated. The PPC porphyrin was chosen due to the structural similarity to the planar PABI molecule. But, exhibiting fluorescence, the PPC porphyrin was chosen to study the impact of encapsulation towards the fluorescent properties of this family of compounds. Indeed the PABI and the PPC molecules possess an aromatic core consisting of 18-π electrons, which emphasise the stability and the electrochromic properties of this family of intensely coloured dyes. The PPC dye exhibits fluorescence whereas the PABI detection was limited to absorption measurements. Excitation and emission spectra of a pure aqueous solution of PPC are illustrated in Figure 6.

Bottom Line: Nevertheless, the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent the encapsulation process from occurring.Mainly, the photophysical characteristics of the dyes are retained upon their encapsulation into the silica matrix, leading to fluorescent silica nanoparticles.This feature article surveys recent research progress on the fabrication strategies of these dye-doped silica nanoparticles.

View Article: PubMed Central - HTML - PubMed

Affiliation: CEA Grenoble, Department of Nano Materials, NanoChemistry and NanoSafety Laboratory (DRT/LITEN/DTNM/LCSN), 17 rue des Martyrs, 38054 Grenoble Cedex 9, France. aurelien.auger@cea.fr.

ABSTRACT
Numerous luminophores may be encapsulated into silica nanoparticles (< 100 nm) using the reverse microemulsion process. Nevertheless, the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent the encapsulation process from occurring. Such nanospheres represent attractive nanoplatforms for the development of biotargeted biocompatible luminescent tracers. Physical and chemical properties of the encapsulated molecules may be affected by the nanomatrix. This study examines the synthesis of different types of dispersed silica nanoparticles, the ability of the selected luminophores towards incorporation into the silica matrix of those nanoobjects as well as the photophysical properties of the produced dye-doped silica nanoparticles. The nanoparticles present mean diameters between 40 and 60 nm as shown by TEM analysis. Mainly, the photophysical characteristics of the dyes are retained upon their encapsulation into the silica matrix, leading to fluorescent silica nanoparticles. This feature article surveys recent research progress on the fabrication strategies of these dye-doped silica nanoparticles.

No MeSH data available.