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Intestine-Specific, Oral Delivery of Captopril/Montmorillonite: Formulation and Release Kinetics

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ABSTRACT

The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14 %w/w and which exhibits near-zero-order release kinetics.

No MeSH data available.


Schematic representation of intercalation of CP into MMT.
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Figure 2: Schematic representation of intercalation of CP into MMT.

Mentions: Three methods (solution, melt and grinding) were employed for the intercalation of CP into the MMT matrix (Figure 2, schematic representation of intercalation process).


Intestine-Specific, Oral Delivery of Captopril/Montmorillonite: Formulation and Release Kinetics
Schematic representation of intercalation of CP into MMT.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3211200&req=5

Figure 2: Schematic representation of intercalation of CP into MMT.
Mentions: Three methods (solution, melt and grinding) were employed for the intercalation of CP into the MMT matrix (Figure 2, schematic representation of intercalation process).

View Article: PubMed Central - HTML - PubMed

ABSTRACT

The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14 %w/w and which exhibits near-zero-order release kinetics.

No MeSH data available.