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Isolated cotton-wool spots of unknown etiology: management and sequential spectral domain optical coherence tomography documentation.

Ioannides A, Georgakarakos ND, Elaroud I, Andreou P - Clin Ophthalmol (2011)

Bottom Line: Clinically they appear as whitish, fluffy patches on the retina and eventually fade with time.Presented here is the work-up and management of this clinical problem for the ophthalmologist.The authors propose that SD-OCT could be a valuable research tool in characterizing and following the dynamic CWS changes at individual retinal layer level, with potential clinical applications as a screening or diagnostic tool in CWS-related diseases.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Mid-Essex Hospitals NHS Trust, Chelmsford.

ABSTRACT
Cotton-wool spots (CWSs) are common retinal manifestations of many diseases including diabetes mellitus, systemic hypertension, and acquired immunodeficiency syndrome. Clinically they appear as whitish, fluffy patches on the retina and eventually fade with time. In this study, spectral domain optical coherence tomography (SD-OCT) with mapping was used to demonstrate in vivo the characteristics of an isolated CWS in a 59-year-old patient as well as its appearance immediately after ophthalmoscopic resolution. Presented here is the work-up and management of this clinical problem for the ophthalmologist. The authors propose that SD-OCT could be a valuable research tool in characterizing and following the dynamic CWS changes at individual retinal layer level, with potential clinical applications as a screening or diagnostic tool in CWS-related diseases.

No MeSH data available.


Related in: MedlinePlus

Left fundus photographs: at presentation showing an isolated cotton-wool spot (A); and 9 weeks later showing resolution (B).
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f1-opth-5-1431: Left fundus photographs: at presentation showing an isolated cotton-wool spot (A); and 9 weeks later showing resolution (B).

Mentions: His uncorrected visual acuities were 20/16 right and 20/20 left. Ocular examination showed an isolated CWS located between his left optic disc and macula (Figure 1A) but no other pathology. His blood pressure was 138/82 mmHg and systemic examination was unremarkable.


Isolated cotton-wool spots of unknown etiology: management and sequential spectral domain optical coherence tomography documentation.

Ioannides A, Georgakarakos ND, Elaroud I, Andreou P - Clin Ophthalmol (2011)

Left fundus photographs: at presentation showing an isolated cotton-wool spot (A); and 9 weeks later showing resolution (B).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3198419&req=5

f1-opth-5-1431: Left fundus photographs: at presentation showing an isolated cotton-wool spot (A); and 9 weeks later showing resolution (B).
Mentions: His uncorrected visual acuities were 20/16 right and 20/20 left. Ocular examination showed an isolated CWS located between his left optic disc and macula (Figure 1A) but no other pathology. His blood pressure was 138/82 mmHg and systemic examination was unremarkable.

Bottom Line: Clinically they appear as whitish, fluffy patches on the retina and eventually fade with time.Presented here is the work-up and management of this clinical problem for the ophthalmologist.The authors propose that SD-OCT could be a valuable research tool in characterizing and following the dynamic CWS changes at individual retinal layer level, with potential clinical applications as a screening or diagnostic tool in CWS-related diseases.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, Mid-Essex Hospitals NHS Trust, Chelmsford.

ABSTRACT
Cotton-wool spots (CWSs) are common retinal manifestations of many diseases including diabetes mellitus, systemic hypertension, and acquired immunodeficiency syndrome. Clinically they appear as whitish, fluffy patches on the retina and eventually fade with time. In this study, spectral domain optical coherence tomography (SD-OCT) with mapping was used to demonstrate in vivo the characteristics of an isolated CWS in a 59-year-old patient as well as its appearance immediately after ophthalmoscopic resolution. Presented here is the work-up and management of this clinical problem for the ophthalmologist. The authors propose that SD-OCT could be a valuable research tool in characterizing and following the dynamic CWS changes at individual retinal layer level, with potential clinical applications as a screening or diagnostic tool in CWS-related diseases.

No MeSH data available.


Related in: MedlinePlus