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A prospective, randomized, fellow eye comparison of WaveLight® Allegretto Wave ® Eye-Q versus VISX CustomVue™ STAR S4 IR™ in laser in situ keratomileusis (LASIK): analysis of visual outcomes and higher order aberrations.

Moshirfar M, Betts BS, Churgin DS, Hsu M, Neuffer M, Sikder S, Church D, Mifflin MD - Clin Ophthalmol (2011)

Bottom Line: Both the WaveLight Allegretto and the VISX CustomVue platforms had equal visual and safety outcomes.Most wavefront optimized HOA values trended upward, with a statistically significant increase in total HOA RMS.Eyes treated with the WF guided platform showed a decreasing trend in HOA values.

View Article: PubMed Central - PubMed

Affiliation: John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. majid.moshirfar@hsc.utah.edu

ABSTRACT

Purpose: To compare outcomes in visual acuity, refractive error, higher-order aberrations (HOAs), contrast sensitivity, and dry eye in patients undergoing laser in situ keratomileusis (LASIK) using wavefront (WF) guided VISX CustomVue and WF optimized WaveLight Allegretto platforms.

Methods: In this randomized, prospective, single-masked, fellow eye study, LASIK was performed on 44 eyes (22 patients), with one eye randomized to WaveLight Allegretto, and the fellow eye receiving VISX CustomVue. Postoperative outcome measures at 3 months included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, root-mean-square (RMS) value of total and grouped HOAs, contrast sensitivity, and Schirmers testing.

Results: Mean values for UDVA (logMAR) were -0.067 ± 0.087 and -0.073 ± 0.092 in the WF optimized and WF guided groups, respectively (P = 0.909). UDVA of 20/20 or better was achieved in 91% of eyes undergoing LASIK with both lasers while UDVA of 20/15 or better was achieved in 64% of eyes using the Allegretto platform, and 59% of eyes using VISX CustomVue (P = 1.000). In the WF optimized group, total HOA increased 4% (P = 0.012), coma increased 11% (P = 0.065), and spherical aberration increased 19% (P = 0.214), while trefoil decreased 5% (P = 0.490). In the WF guided group, total HOA RMS decreased 9% (P = 0.126), coma decreased 18% (P = 0.144), spherical aberration decreased 27% (P = 0.713) and trefoil decreased 19% (P = 0.660). One patient lost one line of CDVA secondary to residual irregular astigmatism.

Conclusion: Both the WaveLight Allegretto and the VISX CustomVue platforms had equal visual and safety outcomes. Most wavefront optimized HOA values trended upward, with a statistically significant increase in total HOA RMS. Eyes treated with the WF guided platform showed a decreasing trend in HOA values.

No MeSH data available.


Related in: MedlinePlus

Comparison of contrast sensitivity between allegretto and VISX laser platforms at 3, 6, 12, and 18 cycles per degree (CPD) preoperatively (n = 22) and at 3 months postoperatively (n = 22) using the Vectrovision CSV-1000E chart (P ≥ 0.066 for all measurements at any time).
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f1-opth-5-1339: Comparison of contrast sensitivity between allegretto and VISX laser platforms at 3, 6, 12, and 18 cycles per degree (CPD) preoperatively (n = 22) and at 3 months postoperatively (n = 22) using the Vectrovision CSV-1000E chart (P ≥ 0.066 for all measurements at any time).

Mentions: Contrast sensitivity did not change significantly in either group when preoperative measurements were compared to postoperative measurements (P ≥ 0.07) (Figure 1).


A prospective, randomized, fellow eye comparison of WaveLight® Allegretto Wave ® Eye-Q versus VISX CustomVue™ STAR S4 IR™ in laser in situ keratomileusis (LASIK): analysis of visual outcomes and higher order aberrations.

Moshirfar M, Betts BS, Churgin DS, Hsu M, Neuffer M, Sikder S, Church D, Mifflin MD - Clin Ophthalmol (2011)

Comparison of contrast sensitivity between allegretto and VISX laser platforms at 3, 6, 12, and 18 cycles per degree (CPD) preoperatively (n = 22) and at 3 months postoperatively (n = 22) using the Vectrovision CSV-1000E chart (P ≥ 0.066 for all measurements at any time).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3198407&req=5

f1-opth-5-1339: Comparison of contrast sensitivity between allegretto and VISX laser platforms at 3, 6, 12, and 18 cycles per degree (CPD) preoperatively (n = 22) and at 3 months postoperatively (n = 22) using the Vectrovision CSV-1000E chart (P ≥ 0.066 for all measurements at any time).
Mentions: Contrast sensitivity did not change significantly in either group when preoperative measurements were compared to postoperative measurements (P ≥ 0.07) (Figure 1).

Bottom Line: Both the WaveLight Allegretto and the VISX CustomVue platforms had equal visual and safety outcomes.Most wavefront optimized HOA values trended upward, with a statistically significant increase in total HOA RMS.Eyes treated with the WF guided platform showed a decreasing trend in HOA values.

View Article: PubMed Central - PubMed

Affiliation: John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. majid.moshirfar@hsc.utah.edu

ABSTRACT

Purpose: To compare outcomes in visual acuity, refractive error, higher-order aberrations (HOAs), contrast sensitivity, and dry eye in patients undergoing laser in situ keratomileusis (LASIK) using wavefront (WF) guided VISX CustomVue and WF optimized WaveLight Allegretto platforms.

Methods: In this randomized, prospective, single-masked, fellow eye study, LASIK was performed on 44 eyes (22 patients), with one eye randomized to WaveLight Allegretto, and the fellow eye receiving VISX CustomVue. Postoperative outcome measures at 3 months included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, root-mean-square (RMS) value of total and grouped HOAs, contrast sensitivity, and Schirmers testing.

Results: Mean values for UDVA (logMAR) were -0.067 ± 0.087 and -0.073 ± 0.092 in the WF optimized and WF guided groups, respectively (P = 0.909). UDVA of 20/20 or better was achieved in 91% of eyes undergoing LASIK with both lasers while UDVA of 20/15 or better was achieved in 64% of eyes using the Allegretto platform, and 59% of eyes using VISX CustomVue (P = 1.000). In the WF optimized group, total HOA increased 4% (P = 0.012), coma increased 11% (P = 0.065), and spherical aberration increased 19% (P = 0.214), while trefoil decreased 5% (P = 0.490). In the WF guided group, total HOA RMS decreased 9% (P = 0.126), coma decreased 18% (P = 0.144), spherical aberration decreased 27% (P = 0.713) and trefoil decreased 19% (P = 0.660). One patient lost one line of CDVA secondary to residual irregular astigmatism.

Conclusion: Both the WaveLight Allegretto and the VISX CustomVue platforms had equal visual and safety outcomes. Most wavefront optimized HOA values trended upward, with a statistically significant increase in total HOA RMS. Eyes treated with the WF guided platform showed a decreasing trend in HOA values.

No MeSH data available.


Related in: MedlinePlus