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Multiple Aspergillus cerebellar abscesses in a middle-aged female: case report and literature review.

Chen S, Pu JL, Yu J, Zhang JM - Int J Med Sci (2011)

Bottom Line: Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary.The possible pathogenesis of this unusual event is discussed.Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

ABSTRACT
Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary. Here, we report the first case of multiple Aspergillus cerebellar abscesses in a 46-year-old female after one mastoidectomy, two craniectomies, and extended use of antibiotics. The possible pathogenesis of this unusual event is discussed. Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

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Histopathology photomicrograph. The cerebellar lesion shows the typical branching septate hyphae of Aspergillus.
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Figure 2: Histopathology photomicrograph. The cerebellar lesion shows the typical branching septate hyphae of Aspergillus.


Multiple Aspergillus cerebellar abscesses in a middle-aged female: case report and literature review.

Chen S, Pu JL, Yu J, Zhang JM - Int J Med Sci (2011)

Histopathology photomicrograph. The cerebellar lesion shows the typical branching septate hyphae of Aspergillus.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3198260&req=5

Figure 2: Histopathology photomicrograph. The cerebellar lesion shows the typical branching septate hyphae of Aspergillus.
Bottom Line: Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary.The possible pathogenesis of this unusual event is discussed.Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

ABSTRACT
Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary. Here, we report the first case of multiple Aspergillus cerebellar abscesses in a 46-year-old female after one mastoidectomy, two craniectomies, and extended use of antibiotics. The possible pathogenesis of this unusual event is discussed. Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

Show MeSH
Related in: MedlinePlus