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Large oncocytic adrenocortical tumor with uncertain malignant potential.

Lee CK, Choi KH, Cha YJ, Bum JH, Lee HH, Kim MS, Park WK, Yang SC, Han WK - Korean J Urol (2011)

Bottom Line: Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid.Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning.Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Urological Science Institute, Yonsei University Health System, Seoul, Korea.

ABSTRACT
Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid. Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning. Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

No MeSH data available.


Related in: MedlinePlus

(A) Typical structure of an oncocytoma with abundant eosinophilic and granular cytoplasm (H&E, ×100). (B, C) Immunohistochemically, the neoplastic cells were positive for histone H3 phosphorylation and vimentin, respectively.
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Figure 2: (A) Typical structure of an oncocytoma with abundant eosinophilic and granular cytoplasm (H&E, ×100). (B, C) Immunohistochemically, the neoplastic cells were positive for histone H3 phosphorylation and vimentin, respectively.

Mentions: Postoperative pathological examination showed necrosis and that less than 25% of the tumor cells were clear cells (Fig. 2A). Immunohistochemical examination showed histone H3 phosphorylation and vimentin positivity (Fig. 2B, C). This case was thus diagnosed as an oncocytic adrenocortical tumor with uncertain malignant potential according to the Weiss system.


Large oncocytic adrenocortical tumor with uncertain malignant potential.

Lee CK, Choi KH, Cha YJ, Bum JH, Lee HH, Kim MS, Park WK, Yang SC, Han WK - Korean J Urol (2011)

(A) Typical structure of an oncocytoma with abundant eosinophilic and granular cytoplasm (H&E, ×100). (B, C) Immunohistochemically, the neoplastic cells were positive for histone H3 phosphorylation and vimentin, respectively.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3198242&req=5

Figure 2: (A) Typical structure of an oncocytoma with abundant eosinophilic and granular cytoplasm (H&E, ×100). (B, C) Immunohistochemically, the neoplastic cells were positive for histone H3 phosphorylation and vimentin, respectively.
Mentions: Postoperative pathological examination showed necrosis and that less than 25% of the tumor cells were clear cells (Fig. 2A). Immunohistochemical examination showed histone H3 phosphorylation and vimentin positivity (Fig. 2B, C). This case was thus diagnosed as an oncocytic adrenocortical tumor with uncertain malignant potential according to the Weiss system.

Bottom Line: Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid.Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning.Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Urological Science Institute, Yonsei University Health System, Seoul, Korea.

ABSTRACT
Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid. Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning. Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

No MeSH data available.


Related in: MedlinePlus