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Large oncocytic adrenocortical tumor with uncertain malignant potential.

Lee CK, Choi KH, Cha YJ, Bum JH, Lee HH, Kim MS, Park WK, Yang SC, Han WK - Korean J Urol (2011)

Bottom Line: Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid.Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning.Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Urological Science Institute, Yonsei University Health System, Seoul, Korea.

ABSTRACT
Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid. Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning. Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

No MeSH data available.


Related in: MedlinePlus

(A) Preoperative computed tomography (CT) findings. The CT image shows a huge, mixed solid and cystic mass lesion in the retroperitoneal space (axial view A-1, coronal view A-2). (B) Gross pathology image of the tumor showing a large, multilobulated, mass-like lesion measuring about 20×18.5×9 cm and weighing 1,700 g.
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Figure 1: (A) Preoperative computed tomography (CT) findings. The CT image shows a huge, mixed solid and cystic mass lesion in the retroperitoneal space (axial view A-1, coronal view A-2). (B) Gross pathology image of the tumor showing a large, multilobulated, mass-like lesion measuring about 20×18.5×9 cm and weighing 1,700 g.

Mentions: A 69-year-old male with no significant medical history presented to the hospital with abdominal discomfort that had lasted for about 1 month. There were no specific findings on the physical examination except for palpation of the abdominal mass. An 18.2×12.3×16.9 cm mixed solid and cystic mass lesion was observed in the retroperitoneal space on a computed tomography (CT) image of the abdomen and pelvis (Fig. 1A). Open abdominal biopsy of the mass was conducted in the hospital in October 2010 and the mass was identified as an adrenocortical neoplasm, but the adrenal mass could not be differentiated from carcinoma or adenoma. The patient was then referred to our hospital for treatment. Preoperative positron emission tomography-CT (PET-CT) showed a huge, necrotic, suprarenal mass with fludeoxyglucose uptake. No sites of suspected distant metastasis were seen. The patient underwent a left radical adrenalectomy, and the mass showed hypervascularity and severe adhesion to the surrounding tissues. The surgical specimen was 20×18.5×9 cm in size and weighed 1,700 g (Fig. 1B).


Large oncocytic adrenocortical tumor with uncertain malignant potential.

Lee CK, Choi KH, Cha YJ, Bum JH, Lee HH, Kim MS, Park WK, Yang SC, Han WK - Korean J Urol (2011)

(A) Preoperative computed tomography (CT) findings. The CT image shows a huge, mixed solid and cystic mass lesion in the retroperitoneal space (axial view A-1, coronal view A-2). (B) Gross pathology image of the tumor showing a large, multilobulated, mass-like lesion measuring about 20×18.5×9 cm and weighing 1,700 g.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3198242&req=5

Figure 1: (A) Preoperative computed tomography (CT) findings. The CT image shows a huge, mixed solid and cystic mass lesion in the retroperitoneal space (axial view A-1, coronal view A-2). (B) Gross pathology image of the tumor showing a large, multilobulated, mass-like lesion measuring about 20×18.5×9 cm and weighing 1,700 g.
Mentions: A 69-year-old male with no significant medical history presented to the hospital with abdominal discomfort that had lasted for about 1 month. There were no specific findings on the physical examination except for palpation of the abdominal mass. An 18.2×12.3×16.9 cm mixed solid and cystic mass lesion was observed in the retroperitoneal space on a computed tomography (CT) image of the abdomen and pelvis (Fig. 1A). Open abdominal biopsy of the mass was conducted in the hospital in October 2010 and the mass was identified as an adrenocortical neoplasm, but the adrenal mass could not be differentiated from carcinoma or adenoma. The patient was then referred to our hospital for treatment. Preoperative positron emission tomography-CT (PET-CT) showed a huge, necrotic, suprarenal mass with fludeoxyglucose uptake. No sites of suspected distant metastasis were seen. The patient underwent a left radical adrenalectomy, and the mass showed hypervascularity and severe adhesion to the surrounding tissues. The surgical specimen was 20×18.5×9 cm in size and weighed 1,700 g (Fig. 1B).

Bottom Line: Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid.Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning.Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Urological Science Institute, Yonsei University Health System, Seoul, Korea.

ABSTRACT
Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid. Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning. Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological evaluation after its resection.

No MeSH data available.


Related in: MedlinePlus